Turnover of Very Low Density Lipoprotein Proteins
1980Measurements of the rate of synthesis and removal, and of the distribution of VLDL within body pools have been derived from analysis of specific radioactivity-time curves after intravenous injections of VLDL radio-labelled in the lipid or protein moieties.
Noel Fidge, Paul J. Nestel
openaire +2 more sources
Kinetics of triglyceride rich lipoproteins: chylomicrons and very low density lipoproteins
Atherosclerosis, 1998Lipoprotein dynamics are complex during the postprandial state. A significant rise in chylomicron concentration is associated with increased competition for LPL with VLDL particles. This results in an increased concentration of large VLDL. The concentration of small VLDL is reduced as a result of diminished conversion of large to small VLDL.
P, Hugh, R, Barrett
openaire +2 more sources
Effect of desialylation of very low-density lipoproteins on their catabolism by lipoprotein lipase
Metabolism, 1985Very low-density lipoproteins (VLDL) contain sialylated apolipoproteins (apo) (eg, apo CIII1-3) that inhibit apo CII activation of lipoprotein lipase (LPL) and also uptake of triglyceride (TG)-rich lipoproteins by the liver. Hypertriglyceridemic patients can have an excess of sialylated apo CIII (apo CIII1 or apo CIII2) in VLDL. These observations have
A.M. Stoline+3 more
openaire +3 more sources
Composition of very low density lipoproteins and in vitro effect of lipoprotein lipase
Clinica Chimica Acta, 1991In order to clarify the relationship between composition and lipolytic responses to lipoprotein lipase (LPL), very low density lipoproteins (VLDL) from rats or humans were incubated with a commercially available LPL or with a partially purified LPL from postheparin human plasma and fatty acids released from VLDL were determined in vitro. VLDL from rats
Kiyohisa Uchida+4 more
openaire +3 more sources
Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein
Biochemical and Biophysical Research Communications, 1972Summary The effects of two apolipoproteins isolated from human very low density lipoproteins (apoLp-Glu and apoLp-Ala) on lipoprotein lipase (LPL) activity have been studied. ApoLp-Glu markedly stimulated LPL as reported by others. ApoLp-Ala isolated by techniques previously described also activated LPL at low levels.
M.L. Baginsky, W. Virgil Brown
openaire +3 more sources
Comparative proteomic profiling of plasma very-low-density and low-density lipoproteins
Clinica Chimica Acta, 2010Low-density lipoprotein (LDL) is a natural metabolite of very-low-density lipoprotein (VLDL) in the circulation. Systematic investigation of total protein components and dynamics might provide insights into this normal metabolic process.VLDL and LDL were purified from normolipidemia pooled plasma by gradient ultracentrifugation with either ionic or non-
Hung Yu Sun+7 more
openaire +3 more sources
Prednisone increases very low density lipoprotein and high density lipoprotein in healthy men
Metabolism, 1988To determine the effect of corticosteroids on lipoprotein metabolism in healthy subjects, we measured lipoprotein lipid and apoprotein levels in eight normolipidemic healthy men before, during, and after administration of oral prednisone 0.35 mg/kg/d.
Walter H. Ettinger, William R. Hazzard
openaire +3 more sources
Very low density lipoprotein metabolism in diabetes mellitus
Diabetes/Metabolism Reviews, 1987The concentration of VLDL and their major lipid, triglyceride, are regulated at many levels from the initial availability of the substrates needed for their synthesis all the way to the function of the enzymes and receptors involved in their removal from plasma.
openaire +3 more sources
Abstract We have demonstrated that low and high density lipoproteins from monkey plasma are capable of accepting and accumulating monoacylglycerol that is formed by the action of lipoprotein lipase on monkey lymph very low density lipoproteins.
Moseley Waite+2 more
openaire +3 more sources
Lipoprotein Metabolism: Chylomicrons, Very-Low-Density Lipoproteins and Low-Density Lipoproteins [PDF]
Audra V. Lembertas, Verne N. Schumaker
openaire +1 more source