Results 71 to 80 of about 14,483,435 (194)

LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives [PDF]

, 2010
Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Charles Coutelle, Harbottle, R, Anna L David, Themis, M, Al-Allaf, FA, Waddington, SN, David, A, Faisal A Al-Allaf, Michael Themis, Coutelle, C, Simon N Waddington, Richard Harbottle   +11 more
core   +1 more source

Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men

Journal of Lipid Research, 2003
Abdominal visceral adipose tissue (AT) accumulation is associated with an atherogenic metabolic profile that includes increased plasma triglyceride (TG), low HDL cholesterol levels, and an insulin-resistant hyperinsulinemic state.
Charles Couillard, Marie-Claude Vohl, James C. Engert, Isabelle Lemieux, Alain Houde, Natalie Alméras, Denis Prud’homme, André Nadeau, Jean-Pierre Després, Jean Bergeron   +9 more
doaj   +1 more source

H.E.L.P. LDL-apheresis clinical experience in Italy

, 2011
H.E.L.P. LDL-apheresis clinical experience in ItalyStefanutti Claudia, Shafii Mahnaz, Di Giacomo Serafina, Morozzi Claudia, Mazzilli Sara and the Italian Multicenter Study on Low-Density-Lipoprotein -Apheresis Working GroupExtracorporeal Therapeutic ...
MOROZZI, CLAUDIA, STEFANUTTI, Claudia, M. Shafii, DI GIACOMO, SERAFINA, The Italian Multicenter Study O. N. Low Density Lipoprotein Apheresis Working Group, S. Mazzilli   +5 more
core   +1 more source

Fatty acids differentially regulate hepatic cholesteryl ester formation and incorporation into lipoproteins in the liver of the mouse

Journal of Lipid Research, 2002
These experiments tested the hypothesis that fatty acids (FAs) that drive cholesterol esterification also enhance sterol secretion and were undertaken using a mouse model where lipoprotein-cholesterol output by the liver could be assessed in vivo.
Chonglun Xie, Laura A. Woollett, Stephen D. Turley, John M. Dietschy   +3 more
doaj   +1 more source

Very Low Density Lipoprotein [PDF]

Journal of Clinical Investigation, 1978
Tova Chajek, Shlomo Eisenberg
openaire   +1 more source

Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice1

Journal of Lipid Research, 2001
Erythropoietic protoporphyria (EPP) is an inherited disorder of heme synthesis caused by deficiency of the mitochondrial enzyme ferrochelatase. EPP in humans is associated with liver disease, hypertriglyceridemia, and a low level of high density ...
Vincent W. Bloks, Torsten Plösch, Harry van Goor, Han Roelofsen, Juul Baller, Rick Havinga, Henkjan J. Verkade, Aad van Tol, Peter L.M. Jansen, Folkert Kuipers   +9 more
doaj   +1 more source

The global, regional, and national burden attributable to low bone mineral density, 1990–2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021

BACKGROUND: Fractures related to osteoporosis and low bone mineral density lead to substantial morbidity, mortality, and cost to individuals and health systems.
GBD 2021 Low Bone Mineral Density Collaborators
core   +1 more source

Protein and cell therapy for lecithin-cholesterol acyltransferase (LCAT) deficiency [PDF]

, 2009
Lecithin-cholesterol acyltransferase (LCAT) is an enzyme principally secreted by the liver into the circulation where it esterifies cholesterol and plays a key role in high- density lipoprotein (HDL) metabolism. In familial and acquired (liver disease)
Low, J K, Low, J.K.
core  

Vector competence of Culex neavei (Diptera: Culicidae) for Usutu virus. [PDF]

, 2012
Usutu virus (USUV), a flavivirus belonging to the Japanese encephalitis serocomplex, was isolated for the first time from a Culex neavei mosquito in 1959 in South Africa. Despite multiple isolations of USUV from Cx.
Boye, Cheikh S, Faye, Ousmane, Nikolay, Birgit, Diallo, Mawlouth, Sall, Amadou A   +4 more
core   +1 more source

Methylation at CPT1A locus is associated with lipoprotein subfraction profiles[S]

Journal of Lipid Research, 2014
Lipoprotein subfractions help discriminate cardiometabolic disease risk. Genetic loci validated as associating with lipoprotein measures do not account for a large proportion of the individual variation in lipoprotein measures.
Alexis C. Frazier-Wood, Stella Aslibekyan, Devin M. Absher, Paul N. Hopkins, Jin Sha, Michael Y. Tsai, Hemant K. Tiwari, Lindsay L. Waite, Degui Zhi, Donna K. Arnett   +9 more
doaj   +1 more source