Results 11 to 20 of about 102,829,138 (255)

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4) [PDF]

, 2012
Proteinase-activated receptors 4 (PAR(4)) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation. Due to the irreversible nature of activation, a fresh
Robben, Joris, Cooke, Alexandra, Gould, Gwyn W., McIntosh, Kathryn A., Gould, Gwyn, Milligan, Graeme, Cunningham, Margaret Rose, Pediani, John D., Cooke, Alexandra E., McIntosh, Kathryn, Nilsson, Mary, Mundell, Stuart, Plevin, Robin, Cunningham, Margaret R., McIntosh, Kathryn A, Pediani, John D, Gould, Gwyn W, Pediani, John, Nilsson, Mary Francis, Cunningham, Margaret R, Cooke, Alexandra E   +20 more
core   +4 more sources

Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion [PDF]

, 2006
The study of ion channels and other membrane proteins and their potential use as biosensors and drug screening targets require their reconstitution in an artificial membrane.
Zagnoni, M, Fisher, K H, Berry, R M, de Planque, M R R, Watts, A, Mendes, G P, Morgan, H, Sandison, M E   +7 more
core   +2 more sources

Munc 18-1 Protein Molecules Move between Membrane Molecular Depots Distinct from Vesicle Docking Sites [PDF]

, 2013
Four evolutionarily conserved proteins are required for mammalian regulated exocytosis: three SNARE proteins, syntaxin, SNAP-25, and synaptobrevin, and the SM protein, Munc18-1. Here, using single-molecule imaging, we measured the spatial distribution of
Rickman, Colin, Lu, Weiping, Yang, Lei, Hamilton, Charlotte, Smyth, Annya M., Cousin, Michael A., Rickman, Colin; id_orcid, Martin, Kirsty J., Duncan, Rory R., Cousin, Michael A.; id_orcid   +9 more
core   +1 more source

Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor-Derived Peptides for Regulation of Mast Cell Degranulation

Frontiers in Immunology, 2018
Vesicle-associated V-soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins and target membrane-associated T-SNAREs (syntaxin 4 and SNAP-23) assemble into a core trans-SNARE complex that mediates membrane fusion during ...
Yoosoo Yang, Yoosoo Yang, Byoungjae Kong, Byoungjae Kong, Younghoon Jung, Younghoon Jung, Joon-Bum Park, Joon-Bum Park, Jung-Mi Oh, Jaesung Hwang, Jae Youl Cho, Jae Youl Cho, Dae-Hyuk Kweon, Dae-Hyuk Kweon   +13 more
doaj   +1 more source

Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting

JCI Insight, 2021
PDCD10, also known as CCM3, is a gene found to be associated with the human disease cerebral cavernous malformations (CCMs). PDCD10 forms a complex with GCKIII kinases including STK24, STK25, and MST4. Studies in C.
Rui Wang, Shi-Ting Wu, Xi Yang, Yude Qian, Jaesung P. Choi, Rui Gao, Siliang Song, Yixuan Wang, Tao Zhuang, Justin J.L. Wong, Yuzhen Zhang, Zhiming Han, Hua A. Lu, Stephen I. Alexander, Renjing Liu, Yin Xia, Xiangjian Zheng   +16 more
doaj   +1 more source

A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]

, 2008
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
core   +1 more source

SNARE Protein Snc1 Is Essential for Vesicle Trafficking, Membrane Fusion and Protein Secretion in Fungi

Cells, 2023
Fungi are an important group of microorganisms that play crucial roles in a variety of ecological and biotechnological processes. Fungi depend on intracellular protein trafficking, which involves moving proteins from their site of synthesis to the final ...
Muhammad Adnan, Waqar Islam, Abdul Waheed, Quaid Hussain, Ling Shen, Juan Wang, Gang Liu   +6 more
doaj   +1 more source

CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]

, 2009
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Borth, Heike, Boekhoff, Ingrid, Ackermann, Frauke, Zitranski, Nele, Gudermann, Thomas, Buech, Thomas   +5 more
core   +1 more source

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]

, 2013
Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Estes, M. K., Guix Arnau, Susana, Katayama, K., Crawford, Sue E., Sharp, T. M.   +4 more
core   +3 more sources

A role for amphiphysin in AP-1/clathrin coat formation [PDF]

, 2013
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. Clathrin, in combination with different adaptor proteins, is the major coat protein for vesicle formation at the plasma membrane, endosomes, and the ...
Huser Studer, Sonja
core   +1 more source