Mover is a homomeric phospho-protein present on synaptic vesicles.
With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. Mover was found in a yeast-2-hybrid assay using the vertebrate-specific
Saheeb Ahmed +9 more
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The road not taken: Less traveled roads from the TGN to the plasma membrane [PDF]
: The trans-Golgi network functions in the distribution of cargo into different transport vesicles that are destined to endosomes, lysosomes and the plasma membrane. Over the years, it has become clear that more than one transport pathway promotes plasma
Anne Spang, Spang, Anne, Spang A
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Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy
Diabetic retinopathy (DR) involves progressive neurovascular degeneration of the retina. Reduction in synaptic protein expression has been observed in retinas from several diabetic animal models and human retinas.
Hugo Ramos +6 more
doaj +1 more source
Studies on interactions of exported "plasmodium falciparum" membrane proteins [PDF]
Responsible for about 700’000 annual deaths worldwide, malaria today is still one of the major health problems in developing countries. The most deadly form of human malaria called malaria tropica is caused by the apicomplexan parasite Plasmodium ...
Dietz, Olivier
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Characterization of VAMP2 in Schistosoma japonicum and the Evaluation of Protective Efficacy Induced by Recombinant SjVAMP2 in Mice. [PDF]
The outer-tegument membrane covering the schistosome is believed to maintain via the fusion of membranous vesicles. Fusion of biological membranes is a fundamental process in all eukaryotic cells driven by formation of trans-SNARE (soluble N ...
Qian Han +10 more
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Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]
The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Weller, U. +11 more
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Head-to-head comparison of available commercial antibodies against Vesicle-associated membrane protein-associated protein B/C (VAPB) by immunoblot (Western blot), immunoprecipitation and immunofluorescence.
Ayoubi, Riham +6 more
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Membrane alterations induced by nonstructural proteins of human norovirus. [PDF]
Human noroviruses (huNoV) are the most frequent cause of non-bacterial acute gastroenteritis worldwide, particularly genogroup II genotype 4 (GII.4) variants.
Sylvie Y Doerflinger +10 more
doaj +1 more source
Human VAMP3 Suppresses or Negatively Regulates Bax Induced Apoptosis in Yeast
Apoptosis is an essential process that is regulated genetically and could lead to a serious disease condition if not well controlled. Bax is one of the main proapoptotic proteins and actively involved in programmed cell death.
Damilare D. Akintade +1 more
doaj +1 more source
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family [PDF]
Background: Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Rodrigues, N.T.L. +11 more
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