Results 41 to 50 of about 268,720 (256)

Fluorescence Resonance Energy Transfer Detection of Synaptophysin I and Vesicle-associated Membrane Protein 2 Interactions during Exocytosis from Single Live Synapses [PDF]

Molecular Biology of the Cell, 2002
To investigate the molecular interactions of synaptophysin I and vesicle-associated membrane protein 2 (VAMP2)/synaptobrevin II during exocytosis, we have used time-lapse videomicroscopy to measure fluorescence resonance energy transfer in live neurons.
PENNUTO M, DUNLAP D, CONTESTABILE A, BENFENATI, FABIO, VALTORTA F.   +4 more
openaire   +4 more sources

Membrane alterations induced by nonstructural proteins of human norovirus. [PDF]

PLoS Pathogens, 2017
Human noroviruses (huNoV) are the most frequent cause of non-bacterial acute gastroenteritis worldwide, particularly genogroup II genotype 4 (GII.4) variants.
Sylvie Y Doerflinger, Mirko Cortese, Inés Romero-Brey, Zach Menne, Thibault Tubiana, Christian Schenk, Peter A White, Ralf Bartenschlager, Stéphane Bressanelli, Grant S Hansman, Volker Lohmann   +10 more
doaj   +1 more source

Human VAMP3 Suppresses or Negatively Regulates Bax Induced Apoptosis in Yeast

Biomedicines, 2021
Apoptosis is an essential process that is regulated genetically and could lead to a serious disease condition if not well controlled. Bax is one of the main proapoptotic proteins and actively involved in programmed cell death.
Damilare D. Akintade, Bhabatosh Chaudhuri   +1 more
doaj   +1 more source

Localization and Function of SolubleN-Ethylmaleimide-sensitive Factor Attachment Protein-25 and Vesicle-associated Membrane Protein-2 in Functioning Gastric Parietal Cells [PDF]

Journal of Biological Chemistry, 2002
The soluble N-ethylmaleimide-sensitive factor attachment protein of 25 kDa (SNAP-25) plays an important role in vesicle trafficking. Together with vesicle-associated membrane protein-2 (VAMP-2) and syntaxin, SNAP-25 forms a ternary complex implicated in docking and fusion of secretory vesicles with the plasma membrane during exocytosis. These so-called
Serhan, Karvar, Xuebiao, Yao, James M, Crothers, Yuechueng, Liu, John G, Forte   +4 more
openaire   +2 more sources

Atlas of interactions between SARS-CoV-2 macromolecules and host proteins

Cell Insight, 2023
The proteins and RNAs of viruses extensively interact with host proteins after infection. We collected and reanalyzed all available datasets of protein-protein and RNA-protein interactions related to SARS-CoV-2.
Guangnan Li, Zhidong Tang, Weiliang Fan, Xi Wang, Li Huang, Yu Jia, Manli Wang, Zhihong Hu, Yu Zhou   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dense core secretory vesicles revealed as a dynamic Ca²⁺store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera [PDF]

The Journal of Cell Biology, 2001
The role of dense core secretory vesicles in the control of cytosolic-free Ca(2+) concentrations ([Ca(2+)](c)) in neuronal and neuroendocrine cells is enigmatic. By constructing a vesicle-associated membrane protein 2-synaptobrevin.aequorin chimera, we show that in clonal pancreatic islet beta-cells: (a) increases in [Ca(2+)](c) cause a prompt increase
MITCHELL KJ, PINTON P, VARADI A, TACCHETTI C, AINSCOW EK, POZZAN, TULLIO, RIZZUTO, ROSARIO, RUTTER G.A.   +7 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

cAMP stimulates exocytic delivery of vesicle‐associated membrane protein 2 in renal epithelial cells (604.6)

The FASEB Journal, 2014
Soluble NSF Attachment Protein Receptors (SNAREs) drive membrane fusion in eukaryotic cells. SNAREs of the Vesicle Associated Membrane Protein (VAMP) family reside in vesicles and mediate vesicle fusion. After fusion, VAMP remains inserted in the plasma membrane until retrieved for another round of fusion.
Paulo Caceres, Pablo Ortiz
openaire   +1 more source

Vesicle-associated Membrane Protein 2 Plays a Specific Role in the Insulin-dependent Trafficking of the Facilitative Glucose Transporter GLUT4 in 3T3-L1 Adipocytes [PDF]

Journal of Biological Chemistry, 1998
Vesicle-associated membrane protein 2 (VAMP2) has been implicated in the insulin-regulated trafficking of GLUT4 in adipocytes. It has been proposed that VAMP2 co-localizes with GLUT4 in a postendocytic storage compartment (Martin, S., Tellam, J., Livingstone, C., Slot, J. W., Gould, G. W., and James, D. E. (1996) J. Cell Biol. 134, 625-635), suggesting
Martin, Laura B., Shewan, Annette, Millar, Caroline A., Gould, Gwyn W., James, David E.   +4 more
openaire   +5 more sources