Results 91 to 100 of about 498,271 (378)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

A Fusion–Growth Protocell Model Based on Vesicle Interactions with Pyrite Particles

open access: yesMolecules
Protocell models play a pivotal role in the exploration of the origin of life. Vesicles are one type of protocell model that have attracted much attention.
Dong Guo   +5 more
doaj   +1 more source

Lipossomas: a bala mágica acertou? Liposomes: has the magic bullet hit the target?

open access: yesQuímica Nova, 2002
Efficient drug delivery systems are as important as drug themselves. A powerful drug unable to reach the target cell is useless in practice. Ehrlich's Magic Bullet was the first carrier system to be proposed.
Nuno C. Santos, Miguel A. R. B. Castanho
doaj   +1 more source

Vesicle dynamics in confined steady and harmonically modulated Poiseuille flows

open access: yes, 2018
We present a numerical study of the time-dependent motion of a two-dimensional vesicle in a channel under an imposed flow. In a Poiseuille flow the shape of the vesicle depends on the flow strength, the mechanical properties of the membrane, and the ...
Benyoussef, Abdelilah   +6 more
core   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Vesicles in magnetic fields [PDF]

open access: yesarXiv, 2016
Liposome vesicles tend to align with an applied magnetic field. This is due to the directional magnetic susceptibility difference of the lipids which form the membrane of these vesicles. In this work a model of liposome vesicles exposed to magnetic field is presented.
arxiv  

Law of corresponding states for osmotic swelling of vesicles

open access: yes, 2012
As solute molecules permeate into a vesicle due to a concentration difference across its membrane, the vesicle swells through osmosis. The swelling can be divided into two stages: (a) an "ironing" stage, where the volume-to-area ratio of the vesicle ...
Angelova   +32 more
core   +1 more source

A Primer on Vesicle Budding [PDF]

open access: yesCell, 1999
A basic scheme of transport vesicle formation is beginning to emerge (Figure 1Figure 1). Its central feature is the priming complex: an association of a small GTPase, a primer protein, and one or several other subunits of the vesicular coat, including a GTPase-activating protein.
Springer, S., Spang, A., Schekman, R.
openaire   +4 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Micro- and Nano-vesicles from First Trimester Human Placentae Carry Flt-1 and Levels Are Increased in Severe Preeclampsia

open access: yesFrontiers in Endocrinology, 2017
Background/objectivesPreeclampsia is a life-threatening hypertensive disease affecting 3–5% of pregnancies. While the pathogenesis of preeclampsia remains unclear, it is known that placenta-derived factors trigger the disease by activating maternal ...
Mancy Tong   +4 more
doaj   +1 more source

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