Results 91 to 100 of about 529,645 (391)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

A Fusion–Growth Protocell Model Based on Vesicle Interactions with Pyrite Particles

open access: yesMolecules
Protocell models play a pivotal role in the exploration of the origin of life. Vesicles are one type of protocell model that have attracted much attention.
Dong Guo   +5 more
doaj   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Micro- and Nano-vesicles from First Trimester Human Placentae Carry Flt-1 and Levels Are Increased in Severe Preeclampsia

open access: yesFrontiers in Endocrinology, 2017
Background/objectivesPreeclampsia is a life-threatening hypertensive disease affecting 3–5% of pregnancies. While the pathogenesis of preeclampsia remains unclear, it is known that placenta-derived factors trigger the disease by activating maternal ...
Mancy Tong   +4 more
doaj   +1 more source

Application of Liposome Technology in the Treatment of Leishmaniasis: Past, Present and Future [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences, 2023
Leishmaniasis is one of the most common parasitic diseases in tropical and subtropical regions worldwide and poses a threat to public health. According to the World Health Organization (WHO), the number of leishmaniasis cases worldwide is estimated at 12
Amir Mellati   +5 more
doaj  

Effect of Interactions Between Anionic Vesicles and a Cationic Terpolymer in Concentrated Solution Regime: Morphology and Size Changes of the Vesicular Particles [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2016
Interactions between polyelectrolytes and oppositely charged vesicular particles have many possible applications in drug delivery or gene therapy. Formation of vesicular structures by 2-(propylcarbamoyl) terephthalic acid heptaisobutyl POSS (POSS DCA) in
Farzad Lahootifard   +2 more
doaj   +1 more source

Vesicles in magnetic fields [PDF]

open access: yesarXiv, 2016
Liposome vesicles tend to align with an applied magnetic field. This is due to the directional magnetic susceptibility difference of the lipids which form the membrane of these vesicles. In this work a model of liposome vesicles exposed to magnetic field is presented.
arxiv  

Synaptic vesicle phosphoproteins and regulation of synaptic function.

open access: yesScience, 1993
Complex brain functions, such as learning and memory, are believed to involve changes in the efficiency of communication between nerve cells. Therefore, the elucidation of the molecular mechanisms that regulate synaptic transmission, the process of ...
P. Greengard   +3 more
semanticscholar   +1 more source

A Primer on Vesicle Budding [PDF]

open access: yesCell, 1999
A basic scheme of transport vesicle formation is beginning to emerge (Figure 1Figure 1). Its central feature is the priming complex: an association of a small GTPase, a primer protein, and one or several other subunits of the vesicular coat, including a GTPase-activating protein.
Springer, S., Spang, A., Schekman, R.
openaire   +4 more sources

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

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