Results 91 to 100 of about 679,023 (353)

Synthetic Vesicle-Based Drug Delivery Systems for Oral Disease Therapy: Current Applications and Future Directions

Journal of Functional Biomaterials
Oral diseases such as dental caries, periodontitis, and oral cancer are prevalent and present significant challenges to global public health. Although these diseases are typically treated through procedures like dental preparation and resin filling ...
Pengjie Huang, Weichang Li, Jiezhong Guan, Yibing Jia, Dan Wang, Yurun Chen, Niu Xiao, Songyue Ou, Yan Wang, Bo Yang   +9 more
doaj   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

The iTRAPs: guardians of synaptic vesicle cargo retrieval during endocytosis

Frontiers in Synaptic Neuroscience, 2016
The reformation of synaptic vesicles during endocytosis is essential for the maintenance of neurotransmission in central nerve terminals. Newly formed synaptic vesicles must be generated with the correct protein cargo in the correct stoichiometry to be ...
Sarah Louise Gordon, Michael Alan Cousin
doaj   +1 more source

Input-Driven Tissue P Automata [PDF]

, 2018
We introduce several variants of input-driven tissue P automata where the rules to be applied only depend on the input symbol. Both strings and multisets are considered as input objects; the strings are either read from an input tape or defined by the
Alhazov, Artiom, Freund, Rudolf, Ivanov, Sergiu, Oswald, Marion, Verlan, Sergey   +4 more
core  

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Intranasal delivery of Salmonella OMVs decorated with Chlamydia trachomatis antigens induces specific local and systemic immune responses

Human Vaccines & Immunotherapeutics
Chlamydia trachomatis is an obligate intracellular pathogen responsible for the most prevalent bacterial sexually transmitted disease globally. The high prevalence of chlamydial infections underscores the urgent need for licensed and effective vaccines ...
Dung T. Huynh, Emanuele Nolfi, Lobna Medfai, Peter van Ulsen, Wouter S. P. Jong, Alice J. A. M. Sijts, Joen Luirink   +6 more
doaj   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

, 2022
Yikun Ju, Yue Hu, Yang Pu, Xiaoyan Xie, Bairong Fang   +4 more
openalex   +1 more source

Giant Unilamellar Vesicle Electroformation: What to Use, What to Avoid, and How to Quantify the Results [PDF]

, 2021
Zvonimir Boban, Ivan Mardešić, Witold K. Subczyński, Marija Raguž   +3 more
openalex   +1 more source

Dynamics of Vesicles in shear and rotational flows: Modal Dynamics and Phase Diagram

, 2011
Despite the recent upsurge of theoretical reduced models for vesicle shape dynamics, comparisons with experiments have not been accomplished. We review the implications of some of the recently proposed models for vesicle dynamics, especially the Tumbling-
Deschamps, Julien, Kantsler, Vasiliy, Segre, Enrico, Steinberg, Victor, Zabusky, Norman J.   +4 more
core   +3 more sources