Results 101 to 110 of about 529,645 (391)

Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Osteoblast-derived extracellular vesicles (EV) are a collection of secreted (sEVs) and matrix-bound nanoparticles that function as foci for mineral nucleation and accumulation.
Owen G. Davies   +9 more
doaj   +1 more source

Vesicle-based artificial cells as chemical microreactors with spatially segregated reaction pathways

open access: yesNature Communications, 2014
In the discipline of bottom-up synthetic biology, vesicles define the boundaries of artificial cells and are increasingly being used as biochemical microreactors operating in physiological environments.
Y. Elani, R. V. Law, O. Ces
semanticscholar   +1 more source

Stability of growing vesicles [PDF]

open access: yesPhysical Review E, 2011
17 pages, 3 ...
Morris, Richard G., McKane, Alan J.
openaire   +5 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Electrohydrodynamic model of vesicle deformation in alternating electric fields [PDF]

open access: yes, 2008
We develop an analytical theory to explain the experimentally-observed morphological transitions of giant vesicles induced by AC electric fields (1). The model treats the inner and suspending media as lossy dielectrics, while the membrane as an ion-impermeable flexible incompressible-fluid sheet.
arxiv   +1 more source

Synaptic vesicle recycling: steps and principles

open access: yesEMBO Journal, 2014
Synaptic vesicle recycling is one of the best‐studied cellular pathways. Many of the proteins involved are known, and their interactions are becoming increasingly clear.
S. Rizzoli
semanticscholar   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

A theoretical study on the dynamics of a compound vesicle in linear shear flow [PDF]

open access: yesarXiv, 2018
The dynamics of a nucleate cell in shear flow is of great relevance in cancer cells and circulatory tumor cells where they dominate the dynamics of blood. Buoyed by the success of Giant Unilamellar vesicles in explaining the dynamics of anucleate cells such as Red Blood cells, compound vesicles have been suggested as a simple model for nucleate cells ...
arxiv  

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release

open access: yesJournal of Cell Biology, 1979
We describe the design and operation of a machine that freezes biological tissues by contact with a cold metal block, which incorporates a timing circuit that stimulates frog neuromuscular junctions in the last few milliseconds before thay are frozen. We
J. Heuser   +5 more
semanticscholar   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

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