Results 111 to 120 of about 529,645 (391)

Synthetic Vesicle-Based Drug Delivery Systems for Oral Disease Therapy: Current Applications and Future Directions

open access: yesJournal of Functional Biomaterials
Oral diseases such as dental caries, periodontitis, and oral cancer are prevalent and present significant challenges to global public health. Although these diseases are typically treated through procedures like dental preparation and resin filling ...
Pengjie Huang   +9 more
doaj   +1 more source

Quantification of mixing in vesicle suspensions using numerical simulations in two dimensions [PDF]

open access: yes, 2016
We study mixing in Stokesian vesicle suspensions in two dimensions on a cylindrical Couette apparatus using numerical simulations. The vesicle flow simulation is done using a boundary integral method and the advection-diffusion equation for the mixing of the solute is solved using a pseudo-spectral scheme.
arxiv   +1 more source

The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins

open access: yesScience, 2014
Introduction The eukaryotic cell contains membrane-bound organelles with distinct functionality and composition. Preservation of organelle identity depends on the highly selective transfer of proteins and lipids between compartments.
Mie Wong, S. Munro
semanticscholar   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Thermodynamic Relaxation Drives Expulsion in Giant Unilamellar Vesicles [PDF]

open access: yesarXiv, 2013
We investigated the thermodynamic relaxation of giant unilamellar vesicles (GUVs) which contained small vesicles within their interior. Quenching these vesicles from their fluid phase (T>Tm) through the phase transition in the gel state (T
arxiv  

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis.

open access: yesAmerican Journal of Human Genetics, 2004
Motor neuron diseases (MNDs) are a group of neurodegenerative disorders with involvement of upper and/or lower motor neurons, such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), progressive bulbar palsy, and primary lateral ...
A. Nishimura   +11 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Equatorial deformation of homogeneous spherical fluid vesicles by a rigid ring [PDF]

open access: yesPhys. Rev. E 111, 035411 (2025)
We examine the deformation of homogeneous spherical fluid vesicles along their equator by a circular rigid ring. We consider deformations preserving the axial and equatorial mirror symmetries of the vesicles. The configurations of the vesicle are determined employing the spontaneous curvature model subject to the constraints imposed by the ring as well
arxiv   +1 more source

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Shape characteristics of the aggregates formed by amphiphilic stars in water: dissipative particle dynamics study

open access: yesCondensed Matter Physics, 2017
We study the effect of the molecular architecture of amphiphilic star polymers on the shape of aggregates they form in water. Both solute and solvent are considered at a coarse-grained level by means of dissipative particle dynamics simulations.
O.Y. Kalyuzhnyi   +2 more
doaj   +1 more source

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