Results 61 to 70 of about 679,023 (353)

Extracellular vesicles

GENETICS
Abstract Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differentiating cells and can rescue damaged cells from toxic or dysfunctional content. EVs can send
Juan Wang, Maureen M Barr, Ann M Wehman
openaire   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Membranolytic Activity of Bile Salts: Influence of Biological Membrane Properties and Composition

Molecules, 2007
The two main steps of the membranolytic activity of detergents: 1) the partitioning of detergent molecules in the membrane and 2) the solubilisation of the membrane are systematically investigated.
Alfred Blume, Katja Knauf, Annegret Hildebrand, Patrick Garidel   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Raspberry vesicles

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2002
We present a method to control the osmotic stress of giant unilamellar vesicles (GUV) and we report an original shrinkage mode of the vesicles: the volume reduction is accompanied by the formation of inverted daughter vesicles which gives the shrunk vesicles the appearance of raspberries.
Bernard, Anne-Laure, Guedeau-Boudeville, Marie-Alice, Jullien, Ludovic, di Meglio, Jean-Marc   +3 more
openaire   +2 more sources

Dynamics of nearly spherical vesicles in an external flow

, 2007
We analytically derive an equation describing vesicle evolution in a fluid where some stationary flow is excited regarding that the vesicle shape is close to a sphere.
E. I. Kats, H. Lamb, J. Meuner, K. S. Turitsyn, R. Dimova, S. S. Vergeles, V. V. Lebedev, V. V. Lebedev, W. Helfrich   +8 more
core   +1 more source

Electrostatic Repulsion of Positively Charged Vesicles and Negatively Charged Objects [PDF]

, 1999
A positively charged, mixed bilayer vesicle in the presence of negatively charged surfaces (for example, colloidal particles) can spontaneously partition into an adhesion zone of definite area, and another zone that repels additional negative objects ...
Aranda-Espinoza, Helim, Chen, Yi, Dan, Nily, Lubensky, TC, Nelson, Philip, Ramos, Laurence, Weitz, DA   +6 more
core   +6 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Hand, foot and mouth disease

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Hand, foot and mouth disease (HFMD) is an acute viral illness with a distinct clinical presentation of oral and characteristic distal extremity lesions. Knowledge of this is important for the dentists as the oral lesions are the first clinical signs and ...
Radhika Muppa, Prameela Bhupatiraju, Mahesh Duddu, Arthi Dandempally   +3 more
doaj   +1 more source

Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles [PDF]

, 1990
Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal ...
Abrahamsson, P., Aumuller, G., Lilja, H., Scheit, K., Seitz, J., von der Kammer, H.   +5 more
core   +2 more sources