Results 81 to 90 of about 521,692 (352)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
A Primer on Vesicle Budding [PDF]
Cell, 1999 A basic scheme of transport vesicle formation is beginning to emerge (Figure 1Figure 1). Its central feature is the priming complex: an association of a small GTPase, a primer protein, and one or several other subunits of the vesicular coat, including a GTPase-activating protein.
Springer, S., Spang, A., Schekman, R.
openaire +4 more sources
Density Functional Simulation of Spontaneous Formation of Vesicle in Block Copolymer Solutions [PDF]
, 2007 We carry out numerical simulations of vesicle formation based on the density functional theory for block copolymer solutions. It is shown by solving the time evolution equations for concentrations that a polymer vesicle is spontaneously formed from the ...
Uneyama, Takashi
core +3 more sources
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Condensed Matter Physics, 2017 We study the effect of the molecular architecture of amphiphilic star polymers on the shape of aggregates they form in water. Both solute and solvent are considered at a coarse-grained level by means of dissipative particle dynamics simulations.
O.Y. Kalyuzhnyi +2 more
doaj +1 more source
Application of Liposome Technology in the Treatment of Leishmaniasis: Past, Present and Future [PDF]
Journal of Mazandaran University of Medical Sciences, 2023 Leishmaniasis is one of the most common parasitic diseases in tropical and subtropical regions worldwide and poses a threat to public health. According to the World Health Organization (WHO), the number of leishmaniasis cases worldwide is estimated at 12
Amir Mellati +5 more
doaj
SnapShot: Extracellular Vesicles
Cell, 2020 Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties.
Federico Cocozza +6 more
openaire +3 more sources
Stability of growing vesicles [PDF]
Physical Review E, 2011 17 pages, 3 ...
Morris, Richard G., McKane, Alan J.
openaire +5 more sources
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2019 Osteoblast-derived extracellular vesicles (EV) are a collection of secreted (sEVs) and matrix-bound nanoparticles that function as foci for mineral nucleation and accumulation.
Owen G. Davies +9 more
doaj +1 more source