Results 251 to 260 of about 152,465 (288)
Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning
Cytoskeleton, EarlyView.ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham +3 more
wiley +1 more source
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
Barrier Immunity, EarlyView.A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background Biomineralization is a vital biological process through which organisms produce mineralized structures such as shells, skeletons, and teeth. Microtubules are essential for biomineralization in various eukaryotic species; however, their specific roles in this process remain unclear.
Areen Qassem +2 more
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Biochemical Society Transactions, 2012
Mutations in LRRK2 (leucine-rich repeat kinase 2) (also known as PARK8 or dardarin) are responsible for the autosomal-dominant form of PD (Parkinson's disease). LRRK2 mutations were found in approximately 3–5% of familial and 1–3% of sporadic PD cases with the highest prevalence (up to 40%) in North Africans and Ashkenazi Jews.
Sanna, G +3 more
openaire +3 more sources
Mutations in LRRK2 (leucine-rich repeat kinase 2) (also known as PARK8 or dardarin) are responsible for the autosomal-dominant form of PD (Parkinson's disease). LRRK2 mutations were found in approximately 3–5% of familial and 1–3% of sporadic PD cases with the highest prevalence (up to 40%) in North Africans and Ashkenazi Jews.
Sanna, G +3 more
openaire +3 more sources
Endocytosis and vesicle trafficking
Current Opinion in Structural Biology, 2002Several common themes have emerged from recent structural and functional studies of proteins involved in the formation of coated vesicles. For example, inositol polyphosphate lipid headgroups are bound specifically by a variety of different domains in ways appropriate to domain function.
Philip R, Evans, David J, Owen
openaire +2 more sources
Endomembranes and vesicle trafficking
Current Opinion in Plant Biology, 1999Over the past year extensive analyses of the accumulated data on the structural and functional organisation of the endomembrane system and vesicular trafficking in higher plants have shown it to be far more complex than previously anticipated. The availability of molecular tools combined with new opportunities to visualise endomembrane dynamics in vivo
C R, Hawes, F, Brandizzi, A V, Andreeva
openaire +2 more sources
Vesicle trafficking in plant immunity
Current Opinion in Plant Biology, 2017To defend against extracellular pathogens, plants primarily depend on cell-autonomous innate immunity due to the lack of the circulatory immune system including mobile immune cells. To extracellularly restrict or kill the pathogens, plant cells dump out antimicrobials. However, since antimicrobials are also toxic to plant cells themselves, they have to
Hye Sup, Yun, Chian, Kwon
openaire +2 more sources
Small GTPases in vesicle trafficking
Current Opinion in Plant Biology, 2004Plant small GTPases belonging to the Rop, Arf, and Rab families are regulators of vesicle trafficking. Rop GTPases regulate actin dynamics and modulate H(2)O(2) production in polar cell growth and pathogen defence. A candidate Rop GDP to Rop GTP exchange factor (RopGEF) SPIKE1 is involved in the morphogenesis of leaf epidermal cells.
MOLENDJIK A. +2 more
openaire +4 more sources
Vesicle trafficking in Arabidopsis pollen tubes
FEBS Letters, 2022The delivery of sperm cells via tip‐growing pollen tubes is an innovation of seed plants and shows the importance of pollen tubes for reproduction and their specific growth kinetics. Fast‐growing pollen tubes demand an extensive and dynamic vesicular trafficking network to build new cell membrane and wall, to deliver proteins among endomembrane ...
Guang‐Jiu Hao +6 more
openaire +2 more sources
Synaptic vesicle trafficking and Parkinson's disease
Developmental Neurobiology, 2011AbstractPresynaptic terminals maintain neurotransmitter release during repeated rounds of stimulation using local recycling of synaptic vesicles (SV). During each SV cycle, protein complex assembly and disassembly results in accumulation of inactive (unfolded) protein intermediates that may render synaptic terminals vulnerable to activity‐dependent ...
Esposito, Giovanni +2 more
openaire +3 more sources