Results 261 to 270 of about 151,771 (292)

VESICLE TRAFFICKING IN CANCER

Scita, G, Disanza, D., Frittoli, E., Palamidessi, A., and Sigismund, S., 2013
Preface.- Clathrin Mediated Endocytosis.- Intimate And Facultative? Regulation Of Clathrin-Mediated Endocytosis By The Actin Cytoskeleton.- Oncogenic Signaling From The Plasma Membrane.- Endocytosis In The Spatial Control Of Polarized Cell Functions.- Aberrant Vesicular Trafficking Contributes To Altered Polarity And Metabolism In Cancer.- Endocytosis ...
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Special delivery: vesicle trafficking in prokaryotes

Molecular Microbiology, 2006
SummaryAlthough the observation that Gram‐negative bacteria produce outer membrane vesicles (MVs) was made over 40 years ago, their biological roles have become a focus of study only within the past 10 years. Recent progress in this area has revealed that bacterial MVs are utilized for several processes including delivery of toxins to eukaryotic cells,
Lauren M, Mashburn-Warren, Marvin, Whiteley   +1 more
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G Proteins and Vesicle Trafficking

Science Signaling, 2001
Attenuating a cellular signal is just as critical as inducing it. For example, regulator of G protein signaling (RGS) proteins modulate the signaling output from receptor-coupled heterotrimeric G proteins. Zheng et al. (see the Perspective by von Zastrow and Mostov) have identified what has been an elusive RGS for ...
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Coordination of COPII vesicle trafficking by Sec23

Trends in Cell Biology, 2008
Coat protein complex II (COPII) is a multi-subunit protein complex responsible for the formation of membrane vesicles at the endoplasmic reticulum. The assembly of this complex on the endoplasmic reticulum membrane needs to be tightly regulated to ensure efficient and specific incorporation of cargo proteins into nascent vesicles.
J Christopher, Fromme, Lelio, Orci, Randy, Schekman   +2 more
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Vesicle trafficking and lipid metabolism in synucleinopathy

Acta Neuropathologica, 2020
The neuronal protein α-synuclein (αS) is central to the pathogenesis of Parkinson's disease and other progressive brain diseases such as Lewy body dementia and multiple system atrophy. These diseases, collectively referred to as 'synucleinopathies', have long been considered purely proteinopathies: diseases characterized by the misfolding of a protein ...
Saranna Fanning, Dennis Selkoe, Ulf Dettmer   +2 more
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Vesicle trafficking and membrane remodelling in cytokinesis

Biochemical Journal, 2011
All cells complete cell division by the process of cytokinesis. At the end of mitosis, eukaryotic cells accurately mark the site of division between the replicated genetic material and assemble a contractile ring comprised of myosin II, actin filaments and other proteins, which is attached to the plasma membrane.
Hélia, Neto, Louise L, Collins, Gwyn W, Gould   +2 more
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Bacterial protein toxins and cell vesicle trafficking

Experientia, 1996
A group of bacterial protein toxins interfere with vesicular trafficking inside cells. Clostridial neurotoxins affect mainly the highly regulated fusion of neurotransmitter- and hormone-containing vesicles with the plasma membrane. They cleave the three SNARE proteins: VAMP, SNAP-25 and syntaxin, and this selective proteolysis results in a blockade of ...
MONTECUCCO, CESARE, PAPINI, EMANUELE, SCHIAVO G.   +2 more
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Rho proteins and vesicle trafficking

2005
Membrane trafficking includes a highly dynamic and intricate set of intracellular pathways responsible for the transport of molecules in and out of the cell, and between the different intracellular compartments. A lot of attention has been paid in the past decades to the role played by distinct classes of small GTPases on the regulation of membrane ...
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Extracellular vesicle–matrix interactions

Nature Reviews Materials, 2023
, Jae-won Shin
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The power of imaging to understand extracellular vesicle biology in vivo

Nature Methods, 2021
Frederik J Verweij, Leonora Balaj, Chantal M Boulanger   +2 more
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