Results 21 to 30 of about 683 (85)

Altered Vesicular Acetylcholine Transporter Expression Regulates Acetylcholine Abundance in the Brain of Drosophila melanogaster

Journal of Neurochemistry, Volume 169, Issue 6, June 2025.
The vesicular acetylcholine transporter (VAChT) packages and transports the neurotransmitter acetylcholine (ACh) into synaptic vesicles for exocytosis, and its activity is necessary for essential life functions such as locomotion and cognition. Yet, the mechanism through which this important protein mediates ACh release is not fully understood. Here we
Rohina A. Nemat, Timothy Chaya, Angeline‐Claudia Atheby, Hakeem O. Lawal   +3 more
wiley   +1 more source

Neuropeptides: The Evergreen Jack‐of‐All‐Trades in Neuronal Circuit Development and Regulation

BioEssays, Volume 47, Issue 3, March 2025.
Neuropeptides provide an efficient alternative to fast neurotransmitters for synapses neurotransmission. Here, a perspective on the roles, eventual redundancy, and receptor‐level signal diversity of neuropeptides during neurodevelopment is provided through galanin as an example. Image shows thalamic neurons in Gal‐Cre:Ai9 mice. Courtesy of J.
Zsofia Hevesi, Tomas Hökfelt, Tibor Harkany   +2 more
wiley   +1 more source

Memantine‐induced functional rewiring of the glutamate synapse in the striatum of dopamine transporter knockout rats

British Journal of Pharmacology, Volume 182, Issue 6, Page 1377-1393, March 2025.
Abstract Background and Purpose Slow‐acting biogenic amines, such as dopamine, are known to modulate fast neurotransmitters e.g. glutamate. In the striatum, dopamine (DA) interacts with glutamate, influencing neural excitability and promoting synaptic plasticity. The exact mechanism of such interaction is not fully understood.
Lucia Caffino, Giorgia Targa, Francesca Mottarlini, Sarah Thielens, Beatrice Rizzi, Agnes Villers, Laurence Ris, Raul R. Gainetdinov, Damiana Leo, Fabio Fumagalli   +9 more
wiley   +1 more source

Point‐of‐Care Health Diagnostics and Food Quality Monitoring by Molecularly Imprinted Polymers‐Based Histamine Sensors

Advanced Sensor Research, Volume 4, Issue 2, February 2025.
This review highlights recent advancements in molecularly imprinted polymers (MIPs) for electrochemical histamine sensing. It covers the selectivity, scalability, and efficiency of MIP sensors in food safety and healthcare. Key topics include histamine metabolism, MIP sensor synthesis and performance, and the integration of these technologies with AI ...
Shahzad Ahmed, Arshiya Ansari, Zhixuan Li, Hirak Mazumdar, Moin Ali Siddiqui, Afzal Khan, Pranay Ranjan, Ajeet Kaushik, Ajayan Vinu, Prashant Kumar   +9 more
wiley   +1 more source

The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina

Advanced Functional Materials, Volume 35, Issue 3, January 15, 2025.
Gene therapy is often the only hope for a cure for many retinal diseases. However, due to the unique anatomy of the eye, the introduction of such genes or nucleic acids is extremely challenging. This article presents various diseases, barriers, and challenges as well as methods and different nanomaterials that are used to deliver nucleic acids into the
José Hurst, Friederike Adams, Sven Schnichels   +2 more
wiley   +1 more source

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

Abstracts

Cancer Science, Volume 116, Issue S1, Page 1-1975, January 2025.
wiley   +1 more source

Neurotransmitter signaling in molecular and behavioral immune responses to pathogens in <i>C. elegans</i>. [PDF]

Microbiol Mol Biol Rev
Otarigho B, Aballay A.
europepmc   +1 more source

Impact of Manganese on Neuronal Function: An Exploratory Multi-Omics Study on Ferroalloy Workers in Brescia, Italy. [PDF]

Brain Sci
Azmoun S, Lewis FC, Shoieb D, Jin Y, Colicino E, Mhatre-Winters I, Gu H, Krishnamurthy H, Richardson JR, Placidi D, Lambertini L, Lucchini RG.   +11 more
europepmc   +1 more source

Biogenic Amine Metabolism and Its Genetic Variations in Autism Spectrum Disorder: A Comprehensive Overview. [PDF]

Biomolecules
Tabolacci C, Caruso A, Micai M, Galati G, Lintas C, Pisanu ME, Scattoni ML.   +6 more
europepmc   +1 more source