Results 41 to 50 of about 149,274 (318)
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has threatened human health and the global economy. Development of additional vaccines and therapeutics is urgently required, but such development with live virus must be ...
Yoichiro Fujioka +7 more
doaj +1 more source
Helical Virus Structure: The Case of the Rhabdovirus Bullet
Commentary on Ge, P.; Tsao, J.; Schein, S.; Green, T.J.; Luo, M.; Zhou, Z.H. Cryo-EM model of the bullet-shaped vesicular stomatitis virus. Science 2010, 327, 689-693.
Jay C. Brown +2 more
doaj +1 more source
Inhibition of translation by poliovirus: Inactivation of a specific initiation factor [PDF]
Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected ...
Baltimore, David +3 more
core +1 more source
The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials
The devastating Ebola virus (EBOV) epidemic in West Africa in 2013–2016 accelerated the progress of several vaccines and antivirals through clinical trials, including the replication-competent vesicular stomatitis virus-based vaccine expressing the EBOV ...
Ellen L. Suder +4 more
semanticscholar +1 more source
Oncolytic viruses, such as vesicular stomatitis virus (VSV), are a promising class of cancer therapeutics. Here the authors report that a mutation in the CSDE1 gene renders cancer cells resistant to VSV replication and oncolysis, but a mutation-derived ...
Timothy Kottke +21 more
doaj +1 more source
Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]
The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
A. V. Boand +25 more
core +1 more source
A two-step lyssavirus real-time polymerase chain reaction using degenerate primers with superior sensitivity to the fluorescent antigen test [PDF]
A generic two-step lyssavirus real-time reverse transcriptase polymerase chain reaction (qRT-PCR), based on a nested PCR strategy, was validated for the detection of different lyssavirus species.
De Craeye, Stéphane +6 more
core +4 more sources
Measuring Genetic Robustness in Vesicular Stomatitis Virus
Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
doaj +1 more source
Eradication of Swine Vesicular Disease in Italy
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba +3 more
doaj +1 more source
Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore [PDF]
Resident integral proteins of the inner nuclear membrane (INM) are synthesized as membrane-integrated proteins on the peripheral endoplasmic reticulum (ER) and are transported to the INM throughout interphase using an unknown trafficking mechanism.
Gerace, Larry +3 more
core +3 more sources

