Results 51 to 60 of about 146,054 (301)

Helical Virus Structure: The Case of the Rhabdovirus Bullet

Viruses, 2010
Commentary on Ge, P.; Tsao, J.; Schein, S.; Green, T.J.; Luo, M.; Zhou, Z.H. Cryo-EM model of the bullet-shaped vesicular stomatitis virus. Science 2010, 327, 689-693.
Jay C. Brown, William W. Newcomb, Gail W. Wertz   +2 more
doaj   +1 more source

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

mBio, 2018
RNA viruses compartmentalize their replication machinery to evade detection by host pattern recognition receptors and concentrate the machinery of RNA synthesis.
Bianca Heinrich, Z. Maliga, D. A. Stein, A. Hyman, S. Whelan   +4 more
semanticscholar   +1 more source

Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in Cancer Therapy

Viruses, 2018
Modern oncotherapy approaches are based on inducing controlled apoptosis in tumor cells. Although a number of apoptosis-induction approaches are available, site-specific delivery of therapeutic agents still remain the biggest hurdle in achieving the ...
S. Bishnoi, Ritudhwaj Tiwari, Sharad Gupta, S. Byrareddy, D. Nayak   +4 more
semanticscholar   +1 more source

Inhibition of translation by poliovirus: Inactivation of a specific initiation factor [PDF]

, 1978
Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected ...
Baltimore, David, Leong, Kahan, Rose, John K., Trachsel, Hans   +3 more
core   +1 more source

Tamoxifen Protects from Vesicular Stomatitis Virus Infection

Pharmaceuticals, 2019
Background: Tamoxifen (TAM) is an estrogen-receptor antagonist, widely used in the adjuvant treatment of early stage estrogen-sensitive breast cancer.
Lamin B. Cham, Sarah-Kim Friedrich, Tom Adomati, Hilal Bhat, Maximilian Schiller, Michael Bergerhausen, Thamer Hamdan, Fanghui Li, Yara Maria Machlah, Murtaza Ali, Vikas Duhan, Karl Sebastian Lang, Justa Friebus-Kardash, Judith Bezgovsek   +13 more
doaj   +1 more source

Eradication of Swine Vesicular Disease in Italy

Viruses, 2020
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba, Francesco Plasmati, Emiliana Brocchi, Luigi Ruocco   +3 more
doaj   +1 more source

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

Nature Communications, 2021
Oncolytic viruses, such as vesicular stomatitis virus (VSV), are a promising class of cancer therapeutics. Here the authors report that a mutation in the CSDE1 gene renders cancer cells resistant to VSV replication and oncolysis, but a mutation-derived ...
Timothy Kottke, Jason Tonne, Laura Evgin, Christopher B. Driscoll, Jacob van Vloten, Victoria A. Jennings, Amanda L. Huff, Brady Zell, Jill M. Thompson, Phonphimon Wongthida, Jose Pulido, Matthew R. Schuelke, Adel Samson, Peter Selby, Elizabeth Ilett, Mark McNiven, Lewis R. Roberts, Mitesh J. Borad, Hardev Pandha, Kevin Harrington, Alan Melcher, Richard G. Vile   +21 more
doaj   +1 more source

Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia.

Blood, 2016
Patients with relapsed acute myeloid leukemia (AML) have limited therapeutic options. Vesicular stomatitis virus (VSV)-interferon β (IFNβ)-sodium iodide symporter (NIS) is an oncolytic VSV encoding IFNβ and the NIS reporter.
Weiwei Shen, M. Patnaik, Autumn J. Ruiz, S. Russell, K. Peng   +4 more
semanticscholar   +1 more source

A two-step lyssavirus real-time polymerase chain reaction using degenerate primers with superior sensitivity to the fluorescent antigen test [PDF]

, 2014
A generic two-step lyssavirus real-time reverse transcriptase polymerase chain reaction (qRT-PCR), based on a nested PCR strategy, was validated for the detection of different lyssavirus species.
De Craeye, Stéphane, Francart, Aurélie, Kalai, Michael, Lamoral, Sophie, Nazé, Florence, Suin, Vanessa, Van Gucht, Steven   +6 more
core   +4 more sources

Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses

Frontiers in Immunology, 2022
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention.
Jie Wang, Zhenyu Lin, Qiuju Liu, Feiyu Fu, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Yuqiang Cheng, Jianhe Sun   +9 more
doaj   +1 more source