Results 51 to 60 of about 149,274 (318)

Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses

Frontiers in Immunology, 2022
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention.
Jie Wang, Zhenyu Lin, Qiuju Liu, Feiyu Fu, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Yuqiang Cheng, Jianhe Sun   +9 more
doaj   +1 more source

Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]

, 1984
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden, Baer, Berke, Cox, Fazekas De, Grimm, Koprowski, Minato, Reddehase, Reddehase, Reddehase, Rosenthal, Rosenthal, Schneider, Sethi, Shope, Shope, Stoker, Taswell, Wiktor, Wiktor, Zinkernagel, Zinkernagel   +22 more
core   +1 more source

Oncolytic Vesicular Stomatitis Virus as a Viro-Immunotherapy: Defeating Cancer with a “Hammer” and “Anvil”

Biomedicines, 2017
Oncolytic viruses have gained much attention in recent years, due, not only to their ability to selectively replicate in and lyse tumor cells, but to their potential to stimulate antitumor immune responses directed against the tumor. Vesicular stomatitis
M. Melzer, Arturo Lopez-Martinez, J. Altomonte   +2 more
semanticscholar   +1 more source

Tamoxifen Protects from Vesicular Stomatitis Virus Infection

Pharmaceuticals, 2019
Background: Tamoxifen (TAM) is an estrogen-receptor antagonist, widely used in the adjuvant treatment of early stage estrogen-sensitive breast cancer.
Lamin B. Cham, Sarah-Kim Friedrich, Tom Adomati, Hilal Bhat, Maximilian Schiller, Michael Bergerhausen, Thamer Hamdan, Fanghui Li, Yara Maria Machlah, Murtaza Ali, Vikas Duhan, Karl Sebastian Lang, Justa Friebus-Kardash, Judith Bezgovsek   +13 more
doaj   +1 more source

Enterovirus vesicular stomatitis with exanthema: Epidemiological Features and Vaccination

Эпидемиология и вакцинопрофилактика, 2022
Relevance. Hand, foot and mouth disease (HFMD) is a disease that is extremely relevant for the Russian Federation. According to modern data, epidemic outbreaks of severe course involving a large number of children are registered in the Russian Federation.
Yu. S. Sytaya, A. Ya. Mindlina
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B., Dong, C., Dong, H., Elliott, R., Li, P.   +4 more
core   +1 more source

Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch [PDF]

, 2010
The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been understood in terms of the classic two-state, concerted model of allosteric regulation.
F. Bai, R. W. Branch, D. V. Nicolau, T. Pilizota, B. C. Steel, P. K. Maini, R. M. Berry, Monod, Duke, Duke, Changeux, Sowa, Cluzel, Bray, Turner, Alon, Kudo, Block, Scharf, Korobkova, Sowa, Ryu, Korobkova, Lapidus, Block, van Albada, Yuan, Karpen, Dyer, Van Way   +29 more
core   +3 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus

STAR Protocols
Summary: Recombinant vectored vaccines provide economical, rapidly engineered, and tailored immunization strategies. Here, we present a protocol for constructing and characterizing recombinant vectored vaccines for rabies virus (RV).
Manar E. Khalifa, Muhammad Munir
doaj   +1 more source

Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors. [PDF]

, 2013
Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery ...
Hwang, B-Y, Schaffer, DV
core