Results 71 to 80 of about 45,278 (218)
Vesicular Stomatitis Virus - Indiana from Colorado, USA 2019
Vesicular stomatitis virus - Indiana isolates collected in Colorado, USA during the 2019 ...
USDA Agricultural Research Service (17475493)
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Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang +10 more
wiley +1 more source
Replication of Vesicular Stomatitis Virus in L Cells [PDF]
Title: Replication of Vesicular Stomatitis Virus in L Cells, Author: Martin Petric, Location: ThodeA heat resistant strain (HR-LT) of the Indiana serotype of vesicular stomatitis virus was characterized.
Petric, Martin
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Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines
Use of the vesicular stomatitis virus (VSV)–based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines’ stability should the cold chain fail.
Derek R. Stein +5 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Quantification of Lyssavirus-Neutralizing Antibodies Using Vesicular Stomatitis Virus Pseudotype Particles [PDF]
Rabies is a highly fatal zoonotic disease which is primarily caused by rabies virus (RABV) although other members of the genus Lyssavirus can cause rabies as well. As yet, 14 serologically and genetically diverse lyssaviruses have been identified, mostly
Zimmer, Gert +9 more
core +1 more source
Postexposure Treatment of Marburg Virus Infection
Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus.
Thomas W. Geisbert +6 more
doaj +1 more source
The synthetic futures of vesicular stomatitis virus [PDF]
Recent advances in synthetic biology have opened up the possibility of finely engineering viral genomes with the goal to understand and prevent viral diseases [1]. Vesicular stomatitis virus (VSV) is one of the most promising viruses for engineering vaccines and oncolytic therapies [2].
Overend, Christopher +2 more
openaire +2 more sources
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Vesicular Stomatitis Virus: Studies of Viral Proteins and Autointerference [PDF]
The long-range aim of this thesis was to further the understanding of the mechanisms involved in virus interference. To this end, biochemical and immunological procedures were used to characterize and define the virus-specific proteins of VSV. Biological
Kang, Chil-Yong
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