Phylogeographic Characterizations of Recent (2015–2023) Senecavirus A Isolates from Canada
VirusesSenecavirus A (SVA) continues to cause vesicular lesions in swine in Canada and many regions worldwide. Since the vesicular lesions caused by SVA are similar to those caused by foot and mouth disease virus, swine vesicular disease virus and vesicular ...
Kate Hole +6 more
doaj +1 more source
Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. [PDF]
, 1992 To understand the interactions between the microtubule-based motor protein kinesin and intracellular components, we have expressed the kinesin heavy chain and its different domains in CV-1 monkey kidney epithelial cells and examined their distributions ...
Bernstein, HD +6 more
core
Viral Evolution and Adaptation as a Multivariate Branching Process
, 2013 In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and ...
Antoneli, Fernando +4 more
core +1 more source
Immune evasion of the CD1d/NKT cell axis [PDF]
, 2018 Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity.
Brutkiewicz, Randy R. +2 more
core +1 more source
Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer
MedComm, Volume 7, Issue 4, April 2026.This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin +10 more
wiley +1 more source
Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals. [PDF]
, 2016 IFIT (interferon-induced with tetratricopeptide repeats) proteins are critical mediators of mammalian innate antiviral immunity. Mouse IFIT1 selectively inhibits viruses that lack 2'O-methylation of their mRNA 5' caps.
Daugherty, Matthew D +3 more
core +1 more source
Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, EarlyView.
Pierre Tiberghien +4 more
wiley +1 more source
Senescent Factors Suppress Innate Antiviral Immunity in Aged Mice via Two Distinct Mechanisms
Aging Cell, Volume 25, Issue 4, April 2026.Four secreted factors from senescent cells, including GDF15, IGF1, IL1α, and IL6, cooperatively suppress antiviral innate immunity. GDF15/IGF1 trigger AKT‐MEK‐mediated inactivation of GSK3β, leading to suppression of the TBK1‐IRF3 axis, whereas IL1α/IL6 induce p52 and RelB to suppress transcription of antiviral genes.
Xu Zhang +4 more
wiley +1 more source
Vesicular Stomatitis Virus Transmission: A Comparison of Incriminated Vectors
Insects, 2018 Vesicular stomatitis (VS) is a viral disease of veterinary importance, enzootic in tropical and subtropical regions of the Americas. In the U.S., VS produces devastating economic losses, particularly in the southwestern states where the outbreaks display
Paula Rozo-Lopez +2 more
doaj +1 more source
Digital detection of biomarkers for low-cost, high-sensitivity diagnostics [PDF]
, 2016 We have demonstrated Interferometric Reflectance Imaging Sensor (IRIS) with the ability to detect single nanoscale particles. By extending single-particle IRIS to in-liquid dynamic imaging, we demonstrated real-time digital detection of individual viral ...
Ünlü, M. Selim
core +1 more source