Results 81 to 90 of about 63,207 (233)
Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit +7 more
doaj +1 more source
Ebola : too far or so close? [PDF]
The year 2014 has witnessed the escalation of the largest ever Ebola outbreak which started in Guinea, and later spread to other countries in West Africa.
Pace, David, Torpiano, Paul
core
Development of the nanobody display technology to target lentiviral vectors to antigen-presenting cells [PDF]
Lentiviral vectors (LVs) provide unique opportunities for the development of immunotherapeutic strategies, as they transduce a variety of cells in situ, including antigen-presenting cells (APCs). Engineering LVs to specifically transduce APCs is required
Breckpot, Karine +10 more
core +1 more source
Harnessing Tumor Organoids to Revolutionize Immunotherapy Research
ABSTRACT Immunotherapy has emerged as a revolutionary approach to cancer treatment, yet the lack of robust preclinical testing platforms impedes progress in this field. Tumor organoids, three‐dimensional structures derived from patient‐specific samples, differ from conventional models by faithfully recapitulating the histological, genetic, and ...
Zhen Wang +7 more
wiley +1 more source
RISK OF INTRODUCING HIGHLY DANGEROUS ANIMAL VESICULAR DISEASES INTO THE RUSSIAN FEDERATION
Animal vesicular diseases are rather widespread in the world. Transboundary vesicular diseases are mainly registered in African and Asian countries. They primarily include foot and mouth disease, sheep and goat pox, peste des petits ruminants, lumpy skin
V. P. Semakina +3 more
doaj +1 more source
Inhibition of translation by poliovirus: Inactivation of a specific initiation factor [PDF]
Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected ...
Baltimore, David +3 more
core +1 more source
A nanofiber filter of quercetin and poly(ethylene oxide), produced through a solution‐blowing technique, serves as an eco‐friendly, high‐performance alternative for antiviral mask filters. The resulting material combines effective particle filtration with excellent breathability, robust mechanical strength, and rapid biodegradability, while also ...
Dogun Park +13 more
wiley +1 more source
Vesicular stomatitis (VS) outbreaks in the western USA occur cyclically, approximately every 8–10 years. Phylogenetic evidence based on a 450 nt region of the P coding sequences suggests that the initial introduction was a single viral lineage closely ...
Rachel Palinski +7 more
doaj +1 more source
The nucleocapsid of vesicular stomatitis virus [PDF]
The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus.
openaire +2 more sources
ABSTRACT Adeno‐associated virus (AAV) gene therapies have achieved some clinical success, with multiple products reaching regulatory approval. Encapsulation of AAV vectors within engineered extracellular vesicles (EVs) is an emerging strategy which could help overcome challenges including pre‐existing anti‐capsid immunity and the need for controlling ...
Jonathan D. Boucher +5 more
wiley +1 more source

