Results 21 to 30 of about 7,934 (212)

Phylodynamics of Alagoas vesiculovirus in Brazil

Brazilian Journal of Microbiology, 2022
The vesicular stomatitis virus belongs to the Rhabdoviridae family, genus Vesiculovirus. Four species (New Jersey, Indiana, Cocal, and Alagoas) are responsible for disease outbreaks in Western Hemisphere countries. In Brazil, the Alagoas virus is responsible for the main outbreaks of the disease, mainly in the states of the Northeast, Midwest, and ...
Antônio Augusto Fonseca Júnior, Mateus Laguardia-Nascimento, Aline Aparecida Silva Barbosa, Valdênia Lopes da Silva Gonçalves, Anapolino Macedo de Oliveira, Anselmo Vasconcelos Rivetti Júnior, Marcelo Fernandes Camargos   +6 more
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A Candidate Multi-Epitope Vaccine Against Pathogenic Chandipura Vesiculovirus Identified using Immunoinformatics. [PDF]

, 2020
Abstract Chandipura vesiculovirus (CHPV) is a rapidly emerging pathogen responsible for causing acute encephalitis. Due to its widespread occurrence in Asian and African countries, this has become a global threat, and there is an urgent need to design an effective and non-allergenic vaccine against this pathogen.
Debashrito Deb, Srijita Basak, Tamalika Kar, Utkarsh Narsaria, Filippo Castiglione, Abhirup Paul, Ashutosh Pandey, Anurag Prakash Srivast   +7 more
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Susceptibility of various animals to the vesiculovirus Piry [PDF]

Journal of Hygiene, 1984
SUMMARYTo determine the pathogenic potential of the vesiculovirus Piry for domestic animals, two ponies, two steers, three sheep, three goats and three pigs were inoculated intradermally in the tongue or, in the case of the pigs, in the snout, heel and coronary band.
C.R. Wilks, J. A. House
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Vesiculovirus Neutralization by Natural IgM and Complement [PDF]

Journal of Virology, 2014
ABSTRACTBecause of its very low human seroprevalence, vesicular stomatitis virus (VSV) has promise as a systemic oncolytic agent for human cancer therapy. However, as demonstrated in this report, the VSV infectious titer drops by 4 log units during the first hour of exposure to nonimmune human serum.
Mulu Z. Tesfay, Arun Ammayappan, Mark J. Federspiel, Glen N. Barber, David F. Stojdl, Kah-Whye Peng, Stephen J. Russell   +6 more
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Structural intermediates in the fusion‐associated transition of vesiculovirus glycoprotein [PDF]

The EMBO Journal, 2017
Vesiculoviruses enter cells by membrane fusion, driven by a large, low-pH-induced, conformational change in the fusion glycoprotein G that involves transition from a trimeric pre-fusion toward a trimeric post-fusion state via monomeric intermediates.
Eduard Baquero, Aurélie Albertini, Hélène Raux, Abbas Abou‐Hamdan, Elisabetta Boeri Erba, Malika Ouldali, Linda Buonocore, John K. Rose, Jean Lepault, Stéphane Bressanelli, Yves Gaudin   +10 more
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Identification and Characterization of MicroRNAs in Snakehead Fish Cell Line upon Snakehead Fish Vesiculovirus Infection [PDF]

International Journal of Molecular Sciences, 2016
MicroRNAs (miRNAs) play important roles in mediating multiple biological processes in eukaryotes and are being increasingly studied to evaluate their roles associated with cellular changes following viral infection. Snakehead fish Vesiculovirus (SHVV) has caused mass mortality in snakehead fish during the past few years.
Xiaodan Liu, Jiagang Tu, Junfa Yuan, Xueqin Liu, Lijuan Zhao, Farman Ullah Dawar, Muhammad Nasir Khan Khattak, Abeer M. Hegazy, Nan Chen, Vikram N. Vakharia, Li Lin   +10 more
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Leader RNA regulates snakehead vesiculovirus replication via interacting with viral nucleoprotein [PDF]

RNA Biology, 2020
Leader RNA, a kind of virus-derived small noncoding RNA, has been proposed to play an important role in regulating virus replication, but the underlying mechanism remains elusive. In this study, snakehead vesiculovirus (SHVV), a kind of fish rhabdovirus causing high mortality to the cultured snakehead fish in China, was used to unveil the molecular ...
Xiangmou Qin, Shuangshuang Feng, Yanwei Zhang, Jianguo Su, Li Lin, Yong‐An Zhang, Jiagang Tu, Yong-an Zhang, Jiagang Tu   +8 more
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Hsp90 Is Required for Snakehead Vesiculovirus Replication via Stabilization of the Viral L Protein

Journal of Virology, 2021
It has long been proposed that cellular proteins are involved in viral RNA synthesis via interacting with the viral polymerase protein. This study focused on identifying cellular proteins interacting with the SHVV L protein, studying the effects of their interactions on SHVV replication, and revealing the underlying mechanisms.
Yanwei Zhang, Yong‐An Zhang, Jiagang Tu, Yong-An Zhang, Jiagang Tu   +4 more
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Development of Vesiculovirus-based Therapeutics for Acute Leukemia

, 2014
Outcomes for most patients with acute leukemia remain dismal. In-vitro, vesiculovirus members induced rapid apoptosis of acute leukemia cells. Intravenous injection of lymphoblastic leukemia cells infected ex-vivo with attenuated Vesicular Stomatitis Virus or Maraba Virus followed by gamma-irradiation, controlled leukemic progression in murine ...
David P. Conrad
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A Pyrido-Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus. [PDF]

J Med Virol
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Plicanti E, Deiana A, Nottoli S, Lottini G, Ibba R, Piras S, Di Marzo C, Vegni S, Lai M, Pistello M, Carta A, Freer G.   +11 more
europepmc   +2 more sources