Inflammatory and neuropathological responses to Vesiculovirus carajas encephalitis in adult mice: variability, tolerance and resistance [PDF]
Frontiers in Cellular and Infection MicrobiologyVesiculovirus carajas (CARV) is a pathogen with neuroinvasive potential, yet its impact on neuroinflammation and sickness behavior remains poorly understood.
Diniz, D G; Diniz, D G; Diniz, Dg; Diniz, Dg; Diniz, Dg; Daniel Guerreiro Diniz; Diniz, Danie
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hnRNPA1 impedes snakehead vesiculovirus replication via competitively disrupting viral phosphoprotein-nucleoprotein interaction and degrading viral phosphoprotein [PDF]
Virulence, 2023 Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) plays an important role in regulating the replication of many viruses. However, it remains elusive whether and how hnRNPA1 regulates fish virus replication.
Jiagang Tu
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Resistance signatures to oncolytic vesiculoviruses in pancreatic ductal adenocarcinoma [PDF]
Molecular Therapy: OncologyPancreatic ductal adenocarcinoma (PDAC) shows limited response to conventional therapies and immunotherapy due to dense stromal barriers and poor immunogenicity.
Chelsae R. Watters +13 more
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Multi-modal efficacy of a chimeric vesiculovirus expressing the Morreton glycoprotein in sarcoma
Molecular Therapy - Oncolytics, 2023 Vesiculoviruses are attractive oncolytic virus platforms due to their rapid replication, appreciable transgene capacity, broad tropism, limited preexisting immunity, and tumor selectivity through type I interferon response defects in malignant cells.
Chelsae R. Watters, Mitesh J Borad
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Broad geographical circulation of a novel vesiculovirus in bats in the Mediterranean region. [PDF]
PLoS Neglected Tropical DiseasesBats are the natural reservoirs for a variety of emerging and re-emerging viruses. Among them, rabies virus (genus Lyssavirus, family Rhabdoviridae) is one of the first and most emblematic described in these animals.
Dong-Sheng Luo +15 more
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Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein [PDF]
FEBS Open BioThe Chandipura virus matrix protein plays a crucial role in virus assembly, budding, and the cytopathic effects observed in infected cells by interacting with several host proteins.
Mariana Grieben
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Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes
Molecular Therapy - Methods and Clinical Development, 2018 Retroviral and lentiviral vectors often use the envelope G protein from the vesicular stomatitis virus Indiana strain (VSVind.G). However, lentivector producer cell lines that stably express VSVind.G have not been reported, presumably because of its ...
Maha Tijani +2 more
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Distinct Lineage of Vesiculovirus from Big Brown Bats, United States
Emerging Infectious Diseases, 2013 We identified a novel rhabdovirus, American bat vesiculovirus, from postmortem tissue samples from 120 rabies-negative big brown bats with a history of human contact. Five percent of the tested bats were infected with this virus.
Terry Fei Fan Ng +2 more
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Molecular Therapy - Nucleic Acids, 2019 Vesicular stomatitis virus Indiana strain glycoprotein (VSVind.G) mediates broad tissue tropism and efficient cellular uptake. Lentiviral vectors (LVs) are particularly promising, as they can efficiently transduce non-dividing cells and facilitate stable
Altar M Munis +2 more
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Antibody landscapes of arboviral exposure across China revealed by high-throughput seroprofiling from a peptide epitope library [PDF]
Infectious Diseases of PovertyBackground Arboviral infections impose significant public health challenges globally, yet routine surveillance typically captures only symptomatic infections, underestimating the true extent of exposure. Insights into how regional and demographic factors
Nan Zhang +9 more
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