Results 21 to 30 of about 7,047 (158)

Hsp90 Is Required for Snakehead Vesiculovirus Replication via Stabilization of the Viral L Protein

Journal of Virology, 2021
It has long been proposed that cellular proteins are involved in viral RNA synthesis via interacting with the viral polymerase protein. This study focused on identifying cellular proteins interacting with the SHVV L protein, studying the effects of their interactions on SHVV replication, and revealing the underlying mechanisms.
Yong-An Zhang, Jiagang Tu
exaly   +4 more sources

Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-envelope Immunity in Lentivector-Based In Vivo Gene Delivery

Molecular Therapy - Nucleic Acids, 2019
Vesicular stomatitis virus Indiana strain glycoprotein (VSVind.G) mediates broad tissue tropism and efficient cellular uptake. Lentiviral vectors (LVs) are particularly promising, as they can efficiently transduce non-dividing cells and facilitate stable
Altar M Munis, Giada Mattiuzzo, Emma M Bentley   +2 more
exaly   +3 more sources

Ginsenoside Rh1 Suppresses Vesicular Stomatitis Virus Replication by Inhibiting Autophagy to Promote Immune Responses [PDF]

Microorganisms
Vesicular stomatitis virus (VSV), a member of the Vesiculovirus genus within the Rhabdoviridae family, is a widespread pathogen affecting all hoofed livestock species, leading to reduced animal growth and productivity.
Hongmei Chen, Qinglu Zhao, Dingcheng Wei, Zhanying Hu, Xueliang Zhu, Rui Zhang   +5 more
doaj   +2 more sources

A Pyrido‐Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus [PDF]

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti, Andrea Deiana, Silvia Nottoli, Giulia Lottini, Roberta Ibba, Sandra Piras, Carlo Di Marzo, Silvia Vegni, Michele Lai, Mauro Pistello, Antonio Carta, Giulia Freer   +11 more
wiley   +2 more sources

Re-emerging Chandipura vesiculovirus: A cause of concern for global health [PDF]

VirusDisease
Chandipura vesiculovirus (CHPV) is an emerging neurotropic virus primarily affecting children and causing acute encephalitis syndrome (AES) in India. The virus, transmitted mainly by sand flies, has led to multiple outbreaks with high mortality rates, particularly in rural and resource-limited settings.
Abhishek Padhi, Ashwini Agarwal, Praggya Mishra, Ekta Gupta, Swatantra Kumar, C. D. S. Katoch, Shailendra K. Saxena   +6 more
openaire   +3 more sources

Antibody landscapes of arboviral exposure across China revealed by high-throughput seroprofiling from a peptide epitope library [PDF]

Infectious Diseases of Poverty
Background Arboviral infections impose significant public health challenges globally, yet routine surveillance typically captures only symptomatic infections, underestimating the true extent of exposure. Insights into how regional and demographic factors
Nan Zhang, Wei Liu, Feng Zhu, Wan Ni Chia, Dai Kuang, Ying Luo, Yuxuan Han, Hua Pei, Lin-Fa Wang, Qianfeng Xia   +9 more
doaj   +2 more sources

Quantification of in vitro replication kinetics of Alagoas vesiculovirus isolates by digital droplet RT-PCR [PDF]

Brazilian Journal of Microbiology, 2023
Vesicular stomatitis caused by Alagoas vesiculovirus (VSAV) has generated disease outbreaks in Brazil, mainly in the northeast region. Phylogenetic studies divide the isolates into three distinct genotypes (A, B, and C). However, there is no description of how this genetic divergence reflects on the phenotype of VSAV isolates such as in vitro ...
Mariana Lázaro Sales, Antônio Augusto Fonseca Júnior, Tatiana Flávia Pinheiro de Oliveira, Amanda de Araújo Lopes, Anselmo Vasconcelos Rivetti Júnior, Marcelo Fernandes Camargos, Jenner Karlisson Pimenta dos Reis   +6 more
openaire   +3 more sources

In silico assessment of 4 methoxypelargonidin and luteolinidin from Parthenium hysterophorous as acetylcholinesterase inhibitors of Phlebotomus Papatasi [PDF]

Scientific Reports
Phlebotomus papatasi is a vector of various health risk diseases, such as sandfly fever and leishmaniasis. Chemical-based insecticides appear to be effective against the vector but are harmful to non-targeted organisms and the environment.
Heena Choudhary, Parshant, Aman Saket, Shivani Singh, Ravi Sankar Kumar.CH, T. Srinivasan, Ravindra Shukla   +6 more
doaj   +2 more sources

MiR-130c-5p targets the SHVV n gene and upregulates immune cytokines (IL-6, IL-22, IL-1β) to inhibit viral replication [PDF]

Frontiers in Immunology
BackgroundSnakehead vesiculovirus (SHVV) has led to huge economic losses in snakehead aquaculture, and its pathogenic mechanisms is still not fully understood.
Jin Wei, Yan Ji, Yaqian Bai, Rui Cheng, Jiaqi Zhang, Xianqin Hu, Chi Zhang   +6 more
doaj   +2 more sources

Phylodynamics of Alagoas vesiculovirus in Brazil

Brazilian Journal of Microbiology, 2022
The vesicular stomatitis virus belongs to the Rhabdoviridae family, genus Vesiculovirus. Four species (New Jersey, Indiana, Cocal, and Alagoas) are responsible for disease outbreaks in Western Hemisphere countries. In Brazil, the Alagoas virus is responsible for the main outbreaks of the disease, mainly in the states of the Northeast, Midwest, and ...
Antônio Augusto, Fonseca Júnior, Mateus, Laguardia-Nascimento, Aline Aparecida Silva, Barbosa, Valdenia Lopes, da Silva Gonçalves, Anapolino Macedo, de Oliveira, Anselmo Vasconcelos, Rivetti Júnior, Marcelo Fernandes, Camargos   +6 more
openaire   +2 more sources