Results 11 to 20 of about 7,047 (158)

Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes [PDF]

open access: yesMolecular Therapy - Methods and Clinical Development, 2018
Retroviral and lentiviral vectors often use the envelope G protein from the vesicular stomatitis virus Indiana strain (VSVind.G). However, lentivector producer cell lines that stably express VSVind.G have not been reported, presumably because of its ...
Maha Tijani   +2 more
exaly   +8 more sources

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein [PDF]

open access: yesFEBS Open Bio
The Chandipura virus matrix protein plays a crucial role in virus assembly, budding, and the cytopathic effects observed in infected cells by interacting with several host proteins.
Mariana Grieben
doaj   +3 more sources

Multi-modal efficacy of a chimeric vesiculovirus expressing the Morreton glycoprotein in sarcoma

open access: yesMolecular Therapy - Oncolytics, 2023
Vesiculoviruses are attractive oncolytic virus platforms due to their rapid replication, appreciable transgene capacity, broad tropism, limited preexisting immunity, and tumor selectivity through type I interferon response defects in malignant cells.
Chelsae R Watters   +2 more
exaly   +5 more sources

Broad geographical circulation of a novel vesiculovirus in bats in the Mediterranean region. [PDF]

open access: yesPLoS Neglected Tropical Diseases
Bats are the natural reservoirs for a variety of emerging and re-emerging viruses. Among them, rabies virus (genus Lyssavirus, family Rhabdoviridae) is one of the first and most emblematic described in these animals.
Dong-Sheng Luo   +15 more
doaj   +4 more sources

Structural intermediates in the fusion‐associated transition of vesiculovirus glycoprotein [PDF]

open access: yesEMBO Journal, 2017
Vesiculoviruses enter cells by membrane fusion, driven by a large, low-pH-induced, conformational change in the fusion glycoprotein G that involves transition from a trimeric pre-fusion toward a trimeric post-fusion state via monomeric intermediates.
Aurélie A Albertini   +2 more
exaly   +5 more sources

Distinct Lineage of Vesiculovirus from Big Brown Bats, United States

open access: yesEmerging Infectious Diseases, 2013
We identified a novel rhabdovirus, American bat vesiculovirus, from postmortem tissue samples from 120 rabies-negative big brown bats with a history of human contact. Five percent of the tested bats were infected with this virus.
Terry Fei Fan Ng   +10 more
doaj   +5 more sources

A real-time reverse transcriptase polymerase chain reaction for detection and quantification of Vesiculovirus [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 2016
Vesiculoviruses (VSV) are zoonotic viruses that cause vesicular stomatitis disease in cattle, horses and pigs, as well as sporadic human cases of acute febrile illness. Therefore, diagnosis of VSV infections by reliable laboratory techniques is important
Aline Lavado Tolardo   +14 more
doaj   +3 more sources

Development of a reverse genetics system for snakehead vesiculovirus (SHVV)

open access: yesVirology, 2019
Snakehead vesiculovirus (SHVV) is a new rhabdovirus isolated from diseased hybrid snakehead fish (Channa maculate ♀ x Channa argus ♂) and has caused serious economic losses in snakehead fish culture in China. To better understand the pathogenicity of SHVV, we developed a reverse genetics system for SHVV by using human and fish cells.
Jianguo Su, Li Lin, Jiagang Tu
exaly   +3 more sources

Resistance signatures to oncolytic vesiculoviruses in pancreatic ductal adenocarcinoma [PDF]

open access: yesMolecular Therapy: Oncology
Pancreatic ductal adenocarcinoma (PDAC) shows limited response to conventional therapies and immunotherapy due to dense stromal barriers and poor immunogenicity.
Chelsae R. Watters   +13 more
doaj   +2 more sources

hnRNPA1 impedes snakehead vesiculovirus replication via competitively disrupting viral phosphoprotein-nucleoprotein interaction and degrading viral phosphoprotein

open access: yesVirulence, 2023
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) plays an important role in regulating the replication of many viruses. However, it remains elusive whether and how hnRNPA1 regulates fish virus replication.
Yong-An Zhang, Jiagang Tu
exaly   +3 more sources

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