Results 121 to 130 of about 480 (154)

Electron beam response corrections for an ultra-high-dose-rate capable diode dosimeter. [PDF]

Med Phys
Dai T, Sloop AM, Schönfeld A, Flatten V, Kozelka J, Hildreth J, Bill S, Sunnerberg JP, Clark MA, Jarvis L, Pogue BW, Bruza P, Gladstone DJ, Zhang R.   +13 more
europepmc   +1 more source

FLASH Radiotherapy and Organelle-Targeted Radiosensitization in Glioblastoma: A Conceptual and Translational Review. [PDF]

Cancers (Basel)
Tang X, Wang X, Xiao K, Zhu B, Lin F, Zhou L.   +5 more
europepmc   +1 more source

Influence of Heterogeneous Media on Very High Energy Electron (VHEE) Dose Penetration and a Monte Carlo-Based Comparison With Existing Radiotherapy Modalities

Nuclear Instruments & Methods in Physics Research B, 2020
• First experimental demonstration of the relative insensitivity of VHEE beams to inhomogeneities. • Topas/GEANT4 simulations on experiments conducted at CERN’s CLEAR facility are in good agreement.
Marcel van Herk, Karen J Kirkby
exaly   +2 more sources

Focused Beam Dosimetry of Short VHEE Bunches [PDF]

Relativistic Plasma Waves and Particle Beams as Coherent and Incoherent Radiation Sources IV, 2021
Accelerators driven by 10s TW-class lasers can produce electron bunches with femtosecond-scale duration and energy of 100s of MeV. A potential application of such short bunches is high-dose rate radiotherapy, which could transition to FLASH radiotherapy if a sufficiently large dose is delivered in a single shot.
Enrico Brunetti, Dino Jaroszynski, Antoine Maitrallain   +2 more
exaly   +4 more sources

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Perspectives in linear accelerator for FLASH VHEE: Study of a compact C-band system

Physica Medica, 2022
In order to translate the FLASH effect in clinical use and to treat deep tumors, Very High Electron Energy irradiations could represent a valid technique. Here, we address the main issues in the design of a VHEE FLASH machine. We present preliminary results for a compact C-band system aiming to reach a high accelerating gradient and high current ...
Faillace L., Alesini D., Bisogni G., Bosco F., Carillo M., Cirrone P., Cuttone G., De Arcangelis D., De Gregorio A., Di Martino F., Favaudon V., Ficcadenti L., Francescone D., Franciosini G., Gallo A., Heinrich S., Migliorati M., Mostacci A., Palumbo L., Patera V., Patriarca A., Pensavalle J., Perondi F., Remetti R., Sarti A., Spataro B., Torrisi G., Vannozzi A., Giuliano L.   +28 more
openaire   +3 more sources

Status of Laser Plasma Accelerator for VHEE-RT

Applying Laser-driven Particle Acceleration II, Medical and Nonmedical Uses of Distinctive Energetic Particle and Photon Sources: SPIE Optics + Optoelectronics Industry Event, 2021
In pioneered works of C. DesRosiers [1] in Radiotherapy (RT) domain, a numerical study of dose deposition conducted with very high energy electron (VHEE) virtual beam and real photon beams has been performed. The conclusion shows that VHEE are providing similar target coverage than X ray, with better sparing of normal tissue in favor of VHEE-RT.
openaire   +1 more source

Dosimetric Evaluation of Very High Energy Electron (VHEE) Beams in the Male Pelvic Region Using Geant4/TOPAS

Atom Indonesia
The CLEAR (CERN Linear Electron Accelerator for Research) facility has significantly advanced high-energy electron radiotherapy, particularly for treating deep-seated tumors.
Mustapha Krim
exaly   +7 more sources

Development of reliable VHEE/FLASH passive dosimetry methods and procedures at CLEAR

2023
The electron beam at CERN Linear Accelerator for Research (CLEAR) has been intensively used to study the potential use of Very High Energy Electrons (VHEE) for radiotherapy, including the so-called FLASH regime. An important part of these studies revolves around the development of reliable dosimetry methods, given that generally accepted standards are ...
Farabolini,Wilfrid, Wroe,Laurence, Rieker,Vilde, Korysko,Pierre, Robertson,Cameron, Corsini,Roberto, Bateman,Joseph   +6 more
openaire   +1 more source

Characteristics of focused very high energy electron (VHEE) beams in radiotherapy

2023
Very High Energy Electron (VHEE) beams represent a promising alternative for treating deep-seated tumors. However, VHEE beams generate quasi-uniform dose distribution along the beam path, leading to healthy tissue overexposed. Focused VHEE beams are a revolutionary radiotherapy technology that enables concentrating doses into a small and well-defined ...
Liu,Zhengzheng, Yang,Zhiyong, Fan,Danlei, Wang,Jian, Fan,Kuanjun   +4 more
openaire   +1 more source

Treatment Planning for Radiotherapy With Very High-Energy Electron Beams and Comparison of VHEE and VMAT Plans

Medical Physics, 2015
Purpose:The aim of this work was to develop a treatment planning workflow for rapid radiotherapy delivered with very high‐energy electron (VHEE) scanning pencil beams of 60–120 MeV and to study VHEE plans as a function of VHEE treatment parameters. Additionally, VHEE plans were compared to clinical state‐of‐the‐art volumetric modulated arc therapy ...
Peter G Maxim, Magdalena Bazalova-Carter
exaly   +3 more sources