Results 121 to 130 of about 381 (150)

A novel fibre optic monitor for VHEE UHDR beam monitoring: first tests at CLEAR [PDF]

, 2023
Beam monitoring for Ultra High Dose Rate (UHDR) radiation therapy using pulsed beams, i.e. Very High Energy Electrons (VHEE), is a major challenge. The lower pulse repetition of VHEE beams means a larger dose-per-pulse is necessary to achieve the mean dose rates required for UHDR therapy (so-called FLASH).
Farabolini,Wilfrid, Buchanan,Emma, Rieker,Vilde, Korysko,Pierre, Ortega Ruiz,Inaki, Corsini,Roberto, Bateman,Joseph, Malyzhenkov,Alexander, Gerbershagen,Alexander, Dosanjh,Manjit   +9 more
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Very-High Energy Electron (VHEE) Studies at CERN's CLEAR User Facility [PDF]

, 2018
Here we investigate how inserts of various densities (0.001-2.2 g/cm³) affect the dose distribution properties of VHEE beams at ~150 MeV. A range variation comparison was also made with clinical proton beams using TOPAS/GEANT4 Monte Carlo simulations.
Lagzda, Agnese, Aitkenhead, Adam, Corsini, Roberto, Farabolini, Wilfrid, Jones, Roger, Kirkby, Karen, MacKay, Ranald, Van Herk, Marcel   +7 more
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Treatment planning for radiotherapy with very high‐energy electron beams and comparison of VHEE and VMAT plans

Medical Physics, 2015
Purpose:The aim of this work was to develop a treatment planning workflow for rapid radiotherapy delivered with very high‐energy electron (VHEE) scanning pencil beams of 60–120 MeV and to study VHEE plans as a function of VHEE treatment parameters. Additionally, VHEE plans were compared to clinical state‐of‐the‐art volumetric modulated arc therapy ...
Magdalena Bazalova-Carter, Peter G Maxim   +1 more
exaly   +3 more sources

Influence of heterogeneous media on Very High Energy Electron (VHEE) dose penetration and a Monte Carlo-based comparison with existing radiotherapy modalities [PDF]

Nuclear Instruments & Methods in Physics Research B, 2020
• First experimental demonstration of the relative insensitivity of VHEE beams to inhomogeneities. • Topas/GEANT4 simulations on experiments conducted at CERN’s CLEAR facility are in good agreement.
Adam Aitkenhead, Karen J Kirkby, Ranald I Mackay   +2 more
exaly   +4 more sources

Development of reliable VHEE/FLASH passive dosimetry methods and procedures at CLEAR

2023
The electron beam at CERN Linear Accelerator for Research (CLEAR) has been intensively used to study the potential use of Very High Energy Electrons (VHEE) for radiotherapy, including the so-called FLASH regime. An important part of these studies revolves around the development of reliable dosimetry methods, given that generally accepted standards are ...
Farabolini,Wilfrid, Wroe,Laurence, Rieker,Vilde, Korysko,Pierre, Robertson,Cameron, Corsini,Roberto, Bateman,Joseph   +6 more
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Characteristics of focused very high energy electron (VHEE) beams in radiotherapy

2023
Very High Energy Electron (VHEE) beams represent a promising alternative for treating deep-seated tumors. However, VHEE beams generate quasi-uniform dose distribution along the beam path, leading to healthy tissue overexposed. Focused VHEE beams are a revolutionary radiotherapy technology that enables concentrating doses into a small and well-defined ...
Liu,Zhengzheng, Yang,Zhiyong, Fan,Danlei, Wang,Jian, Fan,Kuanjun   +4 more
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VHEE and ultra high dose rate radiotherapy studies in the CLEAR user facility

2023
Given the current availability of high-gradient accelerator technology for cost effective and compact electron LINACs in the 100-200 MeV energy range, using Very High Energy Electron (VHEE) radiotherapy (RT) for cancer treatment recently gained a lot of interest. The Ultra High Dose Rate (UHDR) or FLASH dose regime, in which cancerous cells are damaged
Farabolini,Wilfrid, Rieker,Vilde, Korysko,Pierre, Corsini,Roberto, Robertson,Cameron, Malyzhenkov,Alexander, Bateman,Joseph, Dosanjh,Manjit   +7 more
openaire   +1 more source

mm-Wave Linac Design for Next Generation VHEE Cancer Therapy Systems

2021
Proceedings of the 12th International Particle Accelerator Conference, IPAC2021, Campinas, SP ...
Snively, Emma, Deering, Kaitlin, Nanni, Emilio   +2 more
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Toward a laser-driven VHEE radiotherapy: Design of a beam focusing system

Il Nuovo Cimento C
Very High Energy Electron (VHEE) radiotherapy offers a promising approach for cancer treatment, enabling deep tumor targeting, reduced normal tissue toxicity, and improved dose delivery precision. This study focuses on the design and optimization of a focusing system for laser-driven VHEE beams.
Panaino, C.M.V., Piccinini, S., Labate, L.U., Gizzi, L.A.   +3 more
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HIGH GRADIENT MM-WAVE LINAC FOR VHEE THERAPY

Physica Medica, 2022
E. Snively, E. Nanni, K. Deering, S. Kuppusamy   +3 more
openaire   +1 more source