Results 61 to 70 of about 480 (154)

Radionuclide production for dose verification in VHEE FLASH radiotherapy

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
This study explores the production of radionuclides in a PMMA (Polymethylmethacrylate) phantom irradiated with Very High Energy Electrons (VHEE) beams as a novel method for dose verification. In this work, Monte Carlo simulation studies using the Geant4 toolkit and experimental measurements with a VHEE beam produced by a laser-plasma accelerator were ...
Francesco Urso   +9 more
openaire   +4 more sources

Compact dose delivery of laser-accelerated high-energy electron beams toward radiotherapy applications

open access: yesPhysical Review Accelerators and Beams
The use of very high-energy electron (VHEE) beams for radiotherapy has been actively studied for over two decades due to their advantageous dose distribution, deep penetration depth, and great potential of ultrahigh dose-rate irradiation. Recently, laser-
Bing Zhou   +6 more
doaj   +1 more source

Cherenkov Telescope Array Observatory: Die Zukunft der Gammaastronomie

open access: yesPhysik in unserer Zeit, Volume 57, Issue 1, Page 10-18, January 2026.
Im Jahr 1989 hat das Wipple‐Observatorium die erste Quelle hochenergetischer Gammastrahlung entdeckt. 2002 waren dann sechs Quellen bekannt, 2024 schon mehr als 300. Und das ist immer noch lediglich die Spitze des Eisbergs in der jungen Geschichte der Gammaastronomie.
Daniela Hadasch, Daniel Mazin
wiley   +1 more source

Dosimetry of very high energy electrons (VHEE) for radiotherapy applications : using radiochromic film measurements and Monte Carlo simulations [PDF]

open access: yes, 2014
Very high energy electrons (VHEE) in the range from 100-250 MeV have the potential of becoming an alternative modality in radiotherapy because of their improved dosimetry properties compared with MV photons from contemporary medical linear accelerators ...
Mendonca, M.S.   +29 more
core  

Dosimetric characterization of the laser-accelerated high-energy electron beam for radiotherapy applications

open access: yesPhysical Review Accelerators and Beams
Radiotherapy utilizing very-high-energy electron (VHEE) beams in the range of 50–300 MeV has gained significant interest over the past two decades due to their advantageous dose characteristics, deep tissue penetration capabilities, and potential for ...
Bing Zhou   +9 more
doaj   +1 more source

Multilevel mortality risk factors among pediatric hematology‐oncology patients with deterioration

open access: yesCancer, Volume 131, Issue 8, 15 April 2025.
Abstract Background Hospitalized pediatric hematology‐oncology patients have frequent clinical deterioration events (CDEs) requiring intensive care unit (ICU) interventions and resulting in high mortality, particularly in resource‐limited settings. This study identifies independent risk factors for CDE mortality in hospitals providing childhood cancer ...
Asya Agulnik   +47 more
wiley   +1 more source

On the acceptance, commissioning, and quality assurance of electron FLASH units

open access: yesMedical Physics, Volume 52, Issue 2, Page 1207-1223, February 2025.
Abstract Background and purpose FLASH or ultra‐high dose rate (UHDR) radiation therapy (RT) has gained attention in recent years for its ability to spare normal tissues relative to conventional dose rate (CDR) RT in various preclinical trials. However, clinical implementation of this promising treatment option has been limited because of the lack of ...
Allison Palmiero   +17 more
wiley   +1 more source

Planning healthy food environments: An analysis of local government municipal public health and wellbeing policy in regional Victoria

open access: yesHealth Promotion Journal of Australia, Volume 36, Issue 1, January 2025.
Abstract Issue Addressed While there has been an increased focus on how local governments can support the creation of healthy food environments through healthy public policy, little is known about how this is reflected in public health policy in regional areas.
Fiona Dangerfield   +3 more
wiley   +1 more source

Monte Carlo calculated absorbed‐dose energy dependence of EBT3 and EBT4 films for 5–200 MeV electrons and 100 keV–15 MeV photons

open access: yesJournal of Applied Clinical Medical Physics, Volume 25, Issue 12, December 2024.
Abstract Purpose To use Monte Carlo simulations to study the absorbed‐dose energy dependence of GAFChromic EBT3 and EBT4 films for 5–200 MeV electron beams and 100 keV–15 MeV photon beams considering two film compositions: a previous EBT3 composition (Bekerat et al.) and the final composition of EBT3/current composition of EBT4 (Palmer et al ...
Nathan Clements   +1 more
wiley   +1 more source

Initial experience with an electron FLASH research extension (FLEX) for the Clinac system

open access: yesJournal of Applied Clinical Medical Physics, Volume 25, Issue 2, February 2024.
Abstract Purpose Radiotherapy delivered at ultra‐high‐dose‐rates (≥40 Gy/s), that is, FLASH, has the potential to effectively widen the therapeutic window and considerably improve the care of cancer patients. The underlying mechanism of the FLASH effect is not well understood, and commercial systems capable of delivering such dose rates are scarce. The
Kyuhak Oh   +23 more
wiley   +1 more source

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