DataSheet1_Treatment planning of intracranial lesions with VHEE: comparing conventional and FLASH irradiation potential with state-of-the-art photon and proton radiotherapy.pdf [PDF]
The treatment of deep-seated tumours with electrons of very high energies (VHEE, 70–150 MeV) has already been explored in the past, suggesting that a dosimetric coverage comparable with state-of-the-art proton (PT) or photon radiotherapy (RT) could be ...
V. Tombolini (16499106) +26 more
core +1 more source
Multilevel mortality risk factors among pediatric hematology‐oncology patients with deterioration
Abstract Background Hospitalized pediatric hematology‐oncology patients have frequent clinical deterioration events (CDEs) requiring intensive care unit (ICU) interventions and resulting in high mortality, particularly in resource‐limited settings. This study identifies independent risk factors for CDE mortality in hospitals providing childhood cancer ...
Asya Agulnik +47 more
wiley +1 more source
Methods for VHEE/FLASH Radiotherapy Studies and High Dose Rate Dosimetry at the CLEAR User Facility [PDF]
The CERN Linear Electron Accelerator for Research (CLEAR), operating since 2017, is a user facility providing electron beams for a varied and large range of experiments. The accelerator can generate a 60-220 MeV electron beam and it was recently selected
Bateman, Joseph +6 more
core +1 more source
Radiotherapy utilizing very-high-energy electron (VHEE) beams in the range of 50–300 MeV has gained significant interest over the past two decades due to their advantageous dose characteristics, deep tissue penetration capabilities, and potential for ...
Bing Zhou +9 more
doaj +1 more source
On the acceptance, commissioning, and quality assurance of electron FLASH units
Abstract Background and purpose FLASH or ultra‐high dose rate (UHDR) radiation therapy (RT) has gained attention in recent years for its ability to spare normal tissues relative to conventional dose rate (CDR) RT in various preclinical trials. However, clinical implementation of this promising treatment option has been limited because of the lack of ...
Allison Palmiero +17 more
wiley +1 more source
Abstract Issue Addressed While there has been an increased focus on how local governments can support the creation of healthy food environments through healthy public policy, little is known about how this is reflected in public health policy in regional areas.
Fiona Dangerfield +3 more
wiley +1 more source
Datasets and figures exploring VHEE on CLARA for manuscript titled: "Potential of CLARA Test Facility for VHEE" [PDF]
Data and scripts used for the figures and analysis performed in the paper "Potential of CLARA Test Facility for VHEE". Input file for BDSIM and the elegant tracking code are included, along with a Mathematica notebook to recreate some of the plots used ...
Boogert, Stewart +2 more
core +1 more source
Dataset for "VHEE beam dosimetry at CERN Linear Electron Accelerator for Research under ultra-high dose rate conditions" [PDF]
Dataset for "VHEE beam dosimetry at CERN Linear Electron Accelerator for Research under ultra-high dose rate conditions" Daniela Poppinga et al 2021 Biomed. Phys. Eng.
Daniela Poppinga
core +1 more source
Abstract Purpose To use Monte Carlo simulations to study the absorbed‐dose energy dependence of GAFChromic EBT3 and EBT4 films for 5–200 MeV electron beams and 100 keV–15 MeV photon beams considering two film compositions: a previous EBT3 composition (Bekerat et al.) and the final composition of EBT3/current composition of EBT4 (Palmer et al ...
Nathan Clements +1 more
wiley +1 more source
Initial experience with an electron FLASH research extension (FLEX) for the Clinac system
Abstract Purpose Radiotherapy delivered at ultra‐high‐dose‐rates (≥40 Gy/s), that is, FLASH, has the potential to effectively widen the therapeutic window and considerably improve the care of cancer patients. The underlying mechanism of the FLASH effect is not well understood, and commercial systems capable of delivering such dose rates are scarce. The
Kyuhak Oh +23 more
wiley +1 more source

