Results 61 to 70 of about 8,233,255 (298)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Comparing Multi-Label Classification Methods for Provisional Biopharmaceutics Class Prediction. [PDF]

, 2014
The biopharmaceutical classification system (BCS) is now well established and utilized for the development and biowaivers of immediate oral dosage forms. The prediction of BCS class can be carried out using multilabel classification.
Taravat Ghafourian, Ghafourian, Taravat, Danielle Newby (1695076), Newby, D., Danielle Newby, Taravat Ghafourian (4466557), Alex Freitas (3762685), Freitas, Alex A., Alex. A. Freitas   +8 more
core   +1 more source

Precancerous lesions of the cervix — aetiology, classification, diagnosis, prevention [PDF]

, 2021
The present review introduces the aetiology and classification of cervical precancers. The principles of diagnosis based on colposcopy are reviewed.
Yordanov, Angel; Department of Gynecologic Oncology, Medical University Pleven, Bulgaria, Kostov, Stoyan; Obstetrics and Gynaecology Clinic, St. Anna University Hospital, Varna, Bulgaria, Slavchev, Stanislav; Medical University, Varna, Bulgaria; Obstetrics and Gynaecology Clinic, St. Anna University Hospital, Varna, Bulgaria, Kornovski, Yavor; Medical University, Varna, Bulgaria; Obstetrics and Gynaecology Clinic, St. Anna University Hospital, Varna, Bulgaria, Ivanova, Yonka; Medical University, Varna, Bulgaria; Obstetrics and Gynaecology Clinic, St. Anna University Hospital, Varna, Bulgaria, Yonka Ivanova, Angel Yordanov, Stanislav Slavchev, Stoyan Kostov, Yavor Kornovski   +9 more
core   +1 more source

ACCELERATED FRACTAL ENCODING VIA DOMAIN CLASSIFICATION

Science Journal of University of Zakho
The story of fractal image compression is that the image to be compressed is partitioned into many blocks (range pool). Domain pool is created from range pool. Then, each range block is compared with all domain blocks, searching for the best match. This
Ziyad T. Najim
doaj   +1 more source

Comparative Document Summarisation via Classification

Proceedings of the AAAI Conference on Artificial Intelligence, 2019
Thispaperconsidersextractivesummarisationinacomparative setting: given two or more document groups (e.g., separated by publication time), the goal is to select a small number of documents that are representative of each group, and also maximally distinguishable from other groups.
Umanga Bista, Alexander Patrick Mathews, Minjeong Shin, Aditya Krishna Menon, Lexing Xie   +4 more
openaire   +3 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Semi-Supervised Hyperspectral Image Classification via Spatial-Regulated Self-Training

Remote Sensing, 2020
Because there are many unlabeled samples in hyperspectral images and the cost of manual labeling is high, this paper adopts semi-supervised learning method to make full use of many unlabeled samples.
Yue Wu, Guifeng Mu, Can Qin, Qiguang Miao, Wenping Ma, Xiangrong Zhang   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Summary of key steps for the proposed classification method via ultrahigh-dimensional gene expressions.

, 2022
Summary of key steps for the proposed classification method via ultrahigh-dimensional gene expressions.
Li-Pang Chen (9747423)
core   +1 more source

On OCT Image Classification via Deep Learning

IEEE Photonics Journal, 2019
Computer-aided diagnosis of retinopathy is a research hotspot in the field of medical image classification. Diabetic macular edema (DME) and age-related macular degeneration (AMD) are two common ocular diseases that can result in partial or complete loss
Depeng Wang, Liejun Wang
doaj   +1 more source