Results 1 to 10 of about 4,725,133 (183)
Hepatitis B virus (HBV) X protein (HBx) is a viral regulatory and multifunctional protein. It is well-known that the canonical HBx reading frame bears two phylogenetically conserved internal in-frame translational initiation codons at Met2 and Met3, thus
Sergio Hernández+5 more
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Dendritic cells (DCs) promote T-cell mediated tolerance to self-antigens and induce inflammation to innocuous-antigens. This dual potential makes DCs fundamental players in inflammatory disorders.
Cristian Doñas+8 more
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Hepatitis B virus (HBV) is an enveloped DNA human virus belonging to the Hepadnaviridae family. Perhaps its main distinguishable characteristic is the replication of its genome through a reverse transcription process. The HBV circular genome encodes only
Rodrigo A. Villanueva, Alejandra Loyola
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Dopaminergic stimulation leads B-cell infiltration into the central nervous system upon autoimmunity
Background Recent evidence has shown dopamine as a major regulator of inflammation. Accordingly, dopaminergic regulation of immune cells plays an important role in the physiopathology of inflammatory disorders.
Carolina Prado+6 more
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The genome streamlining theory suggests that reduction of microbial genome size optimizes energy utilization in stressful environments. Although this hypothesis has been explored in several cases of low-nutrient (oligotrophic) and high-temperature ...
Diego Cortez+5 more
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Since the beginning of 2020, worldwide attention has been focused on SARS-CoV-2, the second strain of the severe acute respiratory syndrome virus.
A. R. Ruiz-Fernández+2 more
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Introdução: O transtorno afetivo bipolar (TAB) é uma condição psiquiátrica complexa, caracterizada por alterações extremas de humor, incluindo episódios de mania e depressão. A relação entre o uso de álcool, drogas e o risco de suicídio em pacientes com
Stéfanie Venturini Fanton+5 more
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Acidithiobacillus albertensis is an extremely acidophilic, mesophilic, obligatory autotrophic sulfur-oxidizer, with potential importance in the bioleaching of sulfidic metal ores, first described in the 1980s. Here we present the draft genome sequence of
Matías Castro+11 more
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Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro
Background The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, apoptosis and invasiveness ...
Nicole Farfán+4 more
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Evaluation of the safety and satisfaction of rheumatic patients with accelerated infliximab infusion
Introduction Infliximab infusion generally occurs in 2–4 h. Recent studies have suggested the possibility of accelerated infusion (1 h) of this drug. Objective To evaluate the safety of accelerated infliximab infusion in patients with rheumatic diseases.
Jozélio Freire de Carvalho+5 more
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