Results 31 to 40 of about 2,258 (135)

Vidarabine encephalopathy. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1984
Vidarabine (adenine arabinoside, ara-a) has been found to be useful in the treatment of various viral infections. Its adverse neurological effects include tremor and encephalopathy. Two cases of vidarabine encephalopathy are reported and the five other cases in the literature are reviewed.
P A, Cullis, R, Cushing
openaire   +2 more sources

Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes

Marine Drugs, 2020
The marine environment is a rich source of biologically active molecules for the treatment of human diseases, especially cancer. The adaptation to unique environmental conditions led marine organisms to evolve different pathways than their terrestrial ...
Marilia Barreca, Virginia Spanò, Alessandra Montalbano, Mercedes Cueto, Ana R. Díaz Marrero, Irem Deniz, Ayşegül Erdoğan, Lada Lukić Bilela, Corentin Moulin, Elisabeth Taffin-de-Givenchy, Filippo Spriano, Giuseppe Perale, Mohamed Mehiri, Ana Rotter, Olivier P. Thomas, Paola Barraja, Susana P. Gaudêncio, Francesco Bertoni   +17 more
doaj   +1 more source

VP37 Protein Inhibitors for Mpox Treatment: Highlights on Recent Advances, Patent Literature, and Future Directions

Biomedicines, 2023
Monkeypox disease (Mpox) has threatened humankind worldwide since mid-2022. The Mpox virus (MpoxV) is an example of Orthopoxviruses (OPVs), which share similar genomic structures. A few treatments and vaccines are available for Mpox.
Shuaibu A. Hudu, Ahmed S. Alshrari, Aiman Al Qtaitat, Mohd Imran   +3 more
doaj   +1 more source

Standardized Polyalthia longifolia leaf extract induces the apoptotic HeLa cells death via microRNA regulation: identification, validation, and therapeutic potential

Frontiers in Pharmacology, 2023
Polyalthia longifolia var. angustifolia Thw. (Annonaceae), is a famous traditional medicinal plant in Asia. Ample data specifies that the medicinal plant P.
Soundararajan Vijayarathna, Chern Ein Oon, Majid Al-Zahrani, Muyassar H. Abualreesh, Yeng Chen, Jagat R. Kanwar, Sumaira Sahreen, Shakira Ghazanfar, Mohd Adnan, Sreenivasan Sasidharan   +9 more
doaj   +1 more source

Determination of Phenolics and Flavonoids of Some Useful Medicinal Plants and Bioassay-Guided Fractionation Substances of Sclerocarya birrea (A. Rich) Hochst Stem (Bark) Extract and Their Efficacy Against Salmonella typhi

Frontiers in Chemistry, 2021
Gallic acid and catechin are the most abundant phenolic and flavonoid contents found in all plant extracts. The contents and the bioassay-guided fractionating substances of the Sclerocarya birrea (A.
Muhammad Salihu Abdallah, Muhammad Salihu Abdallah, Muskhazli Mustafa, Meenakshii A/P. Nallappan, Sangho Choi, Jin-Hyub Paik, Go Rusea   +6 more
doaj   +1 more source

Recent Advances in Molecular Docking for the Research and Discovery of Potential Marine Drugs

Marine Drugs, 2020
Marine drugs have long been used and exhibit unique advantages in clinical practices. Among the marine drugs that have been approved by the Food and Drug Administration (FDA), the protein–ligand interactions, such as cytarabine–DNA polymerase, vidarabine–
Guilin Chen, Armel Jackson Seukep, Mingquan Guo   +2 more
doaj   +1 more source

Modern approaches to the treatment of herpetic infection in children

Aktualʹnaâ Infektologiâ, 2019
It is currently known 8 pathogenic herpesviruses: two types of herpes simplex virus (HSV-1, HSV-2), varicella zoster virus, Epstein-Barr virus, cytomegalovirus, HHV-6, HHV-7, and HHV-8.
S.O. Kramarov, V.V. Yevtushenko
doaj   +1 more source

Biologically active substances from water invertebrates: a review

Veterinární Medicína, 2012
Some species of invertebrates especially bryozoans (Bryozoa syn. Ectoprocta) and marine sponges (Porifera) are very important sources of pharmacologically exploitable compounds.
J. Sinko, J. Rajchard, Z. Balounova, L. Fikotova   +3 more
doaj   +1 more source

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir

IET Nanobiotechnology, Volume 2026, Issue 1, 2026.
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Abdulhussain Kadhim Jwaziri, Pegah Khales, Seyed Jalal Kiani, Homayoun Yaghouti, Roghayeh Babaei, Zahra Salavatiha, Ahmad Tavakoli, Akon Higuchi   +7 more
wiley   +1 more source

In vitro activity of six antiviral drugs against equid alphaherpesvirus type 1 indicates ganciclovir as promising drug for in vivo studies

Ciência Rural, 2018
: Equid alphaherpesvirus type 1 (EHV-1) is distributed worldwide and is a major agent of abortion, respiratory and neurological disease in horses. No specific treatment is available for EHV-1 infection, yet the potential of antiviral therapy has been ...
Amanda Lovato de Oliveira, Juliana Felipetto Cargnelutti, Ana Paula Gnocato Mortari, Eduardo Furtado Flores, Rudi Weiblen   +4 more
doaj   +1 more source