Results 61 to 70 of about 2,726 (170)

Production of Value-Added Arabinofuranosyl Nucleotide Analogues from Nucleoside by an In Vitro Enzymatic Synthetic Biosystem

Biomolecules
Arabinofuranosyl nucleotide analogue (arabinoside) and the derived compounds, a family of nucleoside analogues, exhibit diverse, typically biological activities and are widely used as antibacterial, antiviral, anti-inflammatory, and antitumor drugs in ...
Yuxue Liu, Xiaojing Zhang, Erchu Yang, Xiaobei Liu, Weiwei Su, Zhenyu Wang, Hailei Wang   +6 more
doaj   +1 more source

Orbital apex syndrome associated with herpes zoster ophthalmicus

Clinical Ophthalmology, 2011
Takuji Kurimoto1, Masahiro Tonari1, Norihiko Ishizaki1, Mitsuhiro Monta2, Saori Hirata2, Hidehiro Oku1, Jun Sugasawa1, Tsunehiko Ikeda11Department of Ophthalmology, Osaka Medical College, 2Department of Ophthalmology, Shitennoji Hospital, Osaka ...
Kurimoto T, Tonari M, Ishizaki N, Monta M, Hirata S, Oku H, Sugasawa J, Ikeda T   +7 more
doaj  

Vidarabine [PDF]

Reactions Weekly, 2020
openaire   +2 more sources

Redesigning the synthesis of Vidarabine via a multienzymatic reaction catalyzed by immobilized nucleoside phosphorylases

, 2015
We here report on the enzymatic synthesis of the antiviral drug Vidarabine (arabinosyladenine, araA) starting from arabinosyluracil and adenine. To this aim, uridine phosphorylase from Clostridium perfringens (CpUP) and a purine nucleoside phosphorylase ...
Alcantara A. R., Bianchi D., UBIALI, DANIELA, Serra I., TERRENI, MARCO, Daly S.   +5 more
core   +1 more source

Concentration-dependent stabilization of UPP1 (A) in the presence of uridine, vidarabine, idoxuridine, trifluridine and fluorouracil; GDA (B) in the presence of guanine, valaciclovir, aciclovir, thioguanine, penciclovir, ganciclovir and mercaptopurine; and concentration dependent destabilization of RRM1 (C) in the presence of azathioprine.

, 2012
Concentration-dependent stabilization of UPP1 (A) in the presence of uridine, vidarabine, idoxuridine, trifluridine and fluorouracil; GDA (B) in the presence of guanine, valaciclovir, aciclovir, thioguanine, penciclovir, ganciclovir and mercaptopurine ...
Louise Egeblad (161722), Jan Balzarini (161754), Pär Nordlund (161768), Staffan Eriksson (161760), Liya Wang (161745), Martin Welin (161726), Susanne Gräslund (161738), Susanne Flodin (161732)   +7 more
core   +1 more source

Physicochemical Study Of The Accelerant Effects Of Dmso On Percutaneous Absorption Of An Antiviral Drug And Other Chemical Prototypes.

, 1983
Vidarabine, an antibiotic nucleoside, has physical properties which tend to limit its passive diffusion through the skin structure and therefore hinder its efficient and adequate topical therapeutic delivery.
Kurihara, Tamie
core   +5 more sources

Studies of chemical distribution and pharmacological activities of porifera-derived alkaloids: A review (2000–2023)

European Journal of Medicinal Chemistry Reports
This review explores the non-random distribution of chemical novelty among marine invertebrate phyla, with a particular focus on Porifera (sponges), which have exhibited the highest average count of novel natural products per species since 1990. Sponges,
Afsona Khatun, Kuntal Hazra, Belarani Mahato, Ritabrata Koley, Rajshekhar Ghorai, Anupam Adhikary, Biplab Debnath, Shaileyee Das   +7 more
doaj   +1 more source

Anti-orthopoxvirus drugs inhibit lumpy skin disease virus replication by targeting viral DNA polymerase.

PLoS Pathogens
Lumpy skin disease (LSD) is an emerging transboundary disease caused by lumpy skin disease virus (LSDV), posing significant threats to global cattle health in the absence of validated drugs. Here, we constructed a recombinant LSDV (rLSDV) expressing both
Zuxin Gong, Jiaqi Dai, Hailong Qu, Yongxin Hu, Fanqi Sun, Chenchen Liu, Xin Li, Chunyan Feng, Zhiliang Wang, Zhen Yang, Gongguan Liu   +10 more
doaj   +1 more source

Synthesis and Preliminary Evaluation of an ASGPr-Targeted Polycationic β-Cyclodextrin Carrier for Nucleosides and Nucleotides

Pharmaceutics
Most antiviral and anticancer nucleosides are prodrugs that require stepwise phosphorylation to their triphosphate nucleotide form for biological activity.
Jang-Ha Ryu, Weizhong Zheng, Xiao-Hong Yang, Hassan Elsaidi, Jim Diakur, Leonard I. Wiebe   +5 more
doaj   +1 more source

A Critical Review on Potentiality of Marine Resources of the Bay of Bengal and Indian Ocean: Bangladesh Perspective

International Journal of Economic and Environment Geology
The Bay of Bengal (BoB) is rich in resources (both living and non-living). Marine living resources include fisheries, mangrove forests, coral ecosystems, plankton, sea grass and seaweeds, etc. Whereas, non-living resources are oil, gas, gas hydrates, sea
Md. Bazlar Rashid, Md. Abdul Aziz Patwary, Md. Shamsuzzaman, Md. Mizanur Rahman   +3 more
doaj   +1 more source