Results 111 to 120 of about 454,759 (354)
Advanced Science, EarlyView.Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang +8 more
wiley +1 more source
Advanced Science, EarlyView.We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
Random Numbers and Gaming [PDF]
, 2017 In Counter Strike: Global Offensive spray pattern control becomes a muscle memory to a player after long periods of playing. It’s a design choice that makes the gunplay between players more about instant crosshair placement with the faster player usually
Baglin, Sinjin
core +1 more source
Advanced Science, EarlyView.Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti +4 more
wiley +1 more source
Research in Psychotherapy, 2016 While many adolescent patients resistantly engage in psychotherapy, they are attracted by new technologies and video games. A development and research project was implemented to design an online adventure video game as a psychotherapeutic tool for ...
Alvaro E. Carrasco
doaj +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
ReS Futurae, 2018 The time travel genre might be considered as one the major science fiction themes, maybe a sub-genre in itself on account of the invariable characteristics of its variations in litterature, cinema - starting in the fifties- and more recently in ...
Clément Personnic, Yannick Kernec’h
doaj +1 more source
Strategies of Collaborative Work in the Classroom through the Design of Video Games. [PDF]
, 2015 Juan Manuel Muñoz González +2 more
openalex +1 more source
The Undermining of Females in Video Games [PDF]
, 2014 Video games as a form of entertainment have been rapidly evolving over the past few decades. Female presence in video games has grown exponentially along side this evolution.
West, Samuel
core +2 more sources