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Visual Function Characteristics in <i>STXBP1</i> Epileptic Encephalopathy Patients. [PDF]
Rosa A +11 more
europepmc +1 more source
Diagnosis and Management of Keppen-Lubinsky Syndrome in a Lebanese Infant: A Case Report. [PDF]
Fakih H.
europepmc +1 more source
The excitatory milieu in glioma: Mechanisms and therapeutic avenues. [PDF]
Khalili BF +8 more
europepmc +1 more source
Pharmacological management of nystagmus: An in-depth review for clinical practice.
Asadigandomani H +4 more
europepmc +1 more source
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Seminars in Pediatric Neurology, 1997
Vigabatrin is a structural analogue of gamma amino butyric acid (GABA), which binds irreversibly to GABA-transaminase causing increased brain levels of GABA. It is an important advance in the medical management of children with epilepsy. It appears to be particularly effective in the treatment of infantile spasms, especially when caused by tuberous ...
W D, Shields, R, Sankar
+5 more sources
Vigabatrin is a structural analogue of gamma amino butyric acid (GABA), which binds irreversibly to GABA-transaminase causing increased brain levels of GABA. It is an important advance in the medical management of children with epilepsy. It appears to be particularly effective in the treatment of infantile spasms, especially when caused by tuberous ...
W D, Shields, R, Sankar
+5 more sources
Epilepsia, 1994
Summary: The discovery of γ‐aminobutyric acid (GABA) as the first major inhibitory neurotransmitter and a program exploring the use of enzyme inhibition as a therapeutic tool provided the basis for the conception of vigabatrin (VGB, Sabril). This molecule, an analogue of GABA, has a highly specific activity as an enzyme‐activated irreversible ...
J P, Mumford, D J, Cannon
+5 more sources
Summary: The discovery of γ‐aminobutyric acid (GABA) as the first major inhibitory neurotransmitter and a program exploring the use of enzyme inhibition as a therapeutic tool provided the basis for the conception of vigabatrin (VGB, Sabril). This molecule, an analogue of GABA, has a highly specific activity as an enzyme‐activated irreversible ...
J P, Mumford, D J, Cannon
+5 more sources

