Results 71 to 80 of about 15,083 (304)
Visual contrast sensitivity in tonic-clonic epileptic patients [PDF]
We measured the effects of epilepsy on visual contrast sensitivity to linear and vertical sine-wave gratings. Sixteen female adults, aged 21 to 50 years, comprised the sample in this study, including eight adults with generalized tonic-clonic seizure ...
ALENCAR, Caroline C. G.+3 more
core +1 more source
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza+4 more
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann+2 more
wiley +1 more source
Epileptic spasms - 175 years on: Trying to teach an old dog new tricks [PDF]
PURPOSE: This text provides an overview of how the condition "infantile spasms" has evolved in the last 175 years. METHOD: Key references are summarised to assimilate this review.
Ibekwe, RC+2 more
core +1 more source
Frontiers in EEG as a tool for the management of pediatric epilepsy: Past, present, and future
Abstract Electroencephalography (EEG) has evolved into an indispensable tool in pediatric epilepsy, fundamentally transforming the diagnosis, classification, and management of this condition. This review chronicles the historical journey of EEG from its groundbreaking inception to its current pivotal role in delineating distinct pediatric epilepsy ...
Hiroki Nariai
wiley +1 more source
The spectrum and efficacy of antiepileptic drugs in patients with infantile spasms in Russia
Recently, the International League Against Epilepsy (ILAE) defined epileptic spasms as a separate type of seizures. According to the international recommendations, the treatment of infantile spasms (IS) begins with hormones or vigabatrin (in the cases ...
T. G. Okhapkina+5 more
doaj +1 more source
Antiepileptic drugs for the treatment of neuropathic pain : a systematic review [PDF]
Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study ...
Gay Escoda, Cosme+3 more
core +1 more source
Vigabatrin and Epilepsy: Lessons Learned [PDF]
Summary: Purpose: The risk factors for visual field loss attributable to vigabatrin (VAVFL) are equivocal. This multinational, prospective, observational study aimed to clarify the principal/major factors for VAVFL. Methods: Interim analysis of three groups with refractory partial epilepsy, stratified by age (8–12 years; >12 years) and exposure to
PERUCCA, EMILIO+8 more
openaire +4 more sources
Abstract Objective Neonatal seizures initiate the onset of epilepsy in less than 20% of cases. Establishing accurate and prompt diagnosis for precision medicine, offering tailored care, and informing families about neurodevelopmental prognosis represents a significant challenge.
Thibault Beretti+8 more
wiley +1 more source
Vigabatrin-Associated “Acute Encephalopathy”
A 6-month-old girl with Alexander disease and hydrocephalus, treated at Children’s Hospital, Tubingen, Germany, developed acute encephalopathy within 3 days of starting vigabatrin (VGB).
J Gordon Millichap
doaj +1 more source