Results 61 to 70 of about 10,435 (208)

The spectrum and efficacy of antiepileptic drugs in patients with infantile spasms in Russia

open access: yesЭпилепсия и пароксизмальные состояния, 2018
Recently, the International League Against Epilepsy (ILAE) defined epileptic spasms as a separate type of seizures. According to the international recommendations, the treatment of infantile  spasms (IS) begins with hormones or vigabatrin (in the cases ...
T. G. Okhapkina   +5 more
doaj   +1 more source

Did the French pregnancy pictogram change antiseizure medication use during pregnancy?

open access: yesEpilepsia, EarlyView.
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo   +7 more
wiley   +1 more source

Vigabatrin-Associated “Acute Encephalopathy”

open access: yesPediatric Neurology Briefs, 2000
A 6-month-old girl with Alexander disease and hydrocephalus, treated at Children’s Hospital, Tubingen, Germany, developed acute encephalopathy within 3 days of starting vigabatrin (VGB).
J Gordon Millichap
doaj   +1 more source

Trends in long-term prescribing of dependence forming medicines [PDF]

open access: yes, 2019
Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S.   +3 more
core  

Visual contrast sensitivity in tonic-clonic epileptic patients [PDF]

open access: yes, 2011
We measured the effects of epilepsy on visual contrast sensitivity to linear and vertical sine-wave gratings. Sixteen female adults, aged 21 to 50 years, comprised the sample in this study, including eight adults with generalized tonic-clonic seizure ...
ALENCAR, Caroline C. G.   +3 more
core   +1 more source

Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add‐on trials in drug‐resistant focal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Most antiseizure medications (ASMs) have been discovered by testing in animal models, which are generally thought to predict antiseizure activity in patients. However, it is not known whether any of these models (or a combination of models) can predict whether a novel ASM exhibits higher clinical efficacy in focal drug‐resistant ...
Wolfgang Löscher, Pavel Klein
wiley   +1 more source

Visual Fields in Mothers and Children Exposed in Utero to Vigabatrin

open access: yesPediatric Neurology Briefs, 2009
Three mothers with 4 children exposed to vigabatrin in utero (but not breast fed) underwent perimetry and imaging of the retinal nerve fiber layer (RNFL) at the University Hospital of Wales and School of Optometry, Cardiff, UK.
J Gordon Millichap
doaj   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin   +3 more
wiley   +1 more source

Developmental Outcomes of Infants Treated With Combination Therapy for Infantile Spasms

open access: yesPediatric Neurology Briefs, 2019
The International Collaborative Infantile Spasms Study (ICISS) Group evaluated the developmental and epilepsy outcomes at 18 months following hormonal treatment alone or hormonal treatment combined with vigabatrin.
Jacqueline Wolak, Sunita N Misra
doaj   +1 more source

Learning lessons from adverse drug reactions in children [PDF]

open access: yes, 2016
Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults.
Bodenstein   +7 more
core   +2 more sources

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