Results 71 to 80 of about 3,513 (158)

Hydrochlorothiazide and risk of hearing disorder: a case series

Journal of Medical Case Reports, 2018
Background Hydrochlorothiazide is not known to cause hearing disorder. The Eritrean Pharmacovigilance Centre, however, has received cases of hearing disorder, including irreversible deafness, associated with hydrochlorothiazide. The aim of this study is,
Natnael Belai, Selamawit Gebrehiwet, Yodit Fitsum, Mulugeta Russom   +3 more
doaj   +1 more source

Sipuleucel‐T associated inflammatory cardiomyopathy: a case report and observations from a large pharmacovigilance database

ESC Heart Failure, 2021
Aims The major cardiovascular (CV) adverse effects observed with sipuleucel‐T from large multi‐institutional clinical trials included thromboembolic events, myocardial infarction, and congestive heart failure in up to 0.3% of patients with CV risk ...
Melissa Y.Y. Moey, Rahim A. Jiwani, Kotaro Takeda, Karyn Prenshaw, R. Wayne Kreeger, John Inzerillo, Darla K. Liles, C. Bogdan Marcu, Bénédicte Lebrun‐Vignes, D. Lynn Morris, Sivakumar Ardhanari, Joe‐Elie Salem   +11 more
doaj   +1 more source

Drug‐Induced Vitiligo: FDA Adverse Events Reporting System (FAERS) and Canada Vigilance Adverse Reaction (CAVR) Database Analysis and Literature Review

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Vitiligo is a common chronic acquired pigmentation disease, that usually occurs with an asymptomatic whitish patch or macule. Although previous studies have reported several cases of drug‐induced vitiligo, there are few comprehensive studies determining the drugs that induce vitiligo.
Yuhao Li, Yi Ou, Luyue Chang, Ruiyao Wang, Xinyi Shao, Jingbo Zhang, Jin Chen   +6 more
wiley   +1 more source

Safety of Biological Medicinal Products for Hereditary Coagulopathies: An Analysis of the Russian Pharmacovigilance Database

Безопасность и риск фармакотерапии
INTRODUCTION. With the expanding product range and the introduction of novel biological medicinal products for haemophilia A, haemophilia B, and von Willebrand disease in the Russian pharmaceutical market, post-marketing safety surveillance becomes ...
D. S. Fokina, O. V. Zhukova, A. L. Khokhlov   +2 more
doaj   +1 more source

Closing the Translational Gap: Closed‐Loop AI Discovery Frameworks for Experimental Validation and Clinical Implementation in Cancer Therapeutics

Cancer Medicine, Volume 15, Issue 8, August 2026.
Artificial intelligence accelerates cancer therapeutic development through an iterative, closed‐loop pipeline: from AI‐driven target and drug discovery, through automated synthesis and screening, to experimental validation in in vivo tumor models, culminating in clinical translation guided by patient data.
Tuğba Ören Varol, Mehmet Varol
wiley   +1 more source

Signal Messages in Pediatric Practice

Безопасность и риск фармакотерапии, 2018
. Detection and analysis of drug safety signals in children is a mandatory part of pharmacovigilance. The criteria for evaluating signals of adverse effects were considered.
G. V. Kutekhova, E. O. Zhuravleva, M. A. Darmostukova, I. I. Snegireva, N. Yu. Velts, R. N. Alyautdin, E. V. Shubnikova   +6 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, Volume 40, Issue 8, Page 4845-4857, August 2026.
ABSTRACT Over the last decade, ashwagandha ( Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, Volume 40, Issue 8, Page 4880-4897, August 2026.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Association Between SGLT2 Inhibitors and DPP‐4 Inhibitors Use and Risk of Acute Pancreatitis: Findings From Nationwide Case‐Based Analyses

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6767-6775, August 2026.
ABSTRACT Aims The Korean national health insurance claims database was utilised to investigate the association between sodium–glucose cotransporter 2 inhibitors (SGLT2i) or dipeptidyl peptidase‐4 inhibitors (DPP‐4i) and the risk of acute pancreatitis (AP). Materials and Methods Patients with type 2 diabetes mellitus prescribed DPP‐4i or SGLT2i at least
Ye‐Jee Kim, Yun Kyung Cho, Mi‐Sook Kim, Joongyub Lee, Seonghae Kim, Bo Ram Yang   +5 more
wiley   +1 more source

Respiratory aspiration during treatment with benzodiazepines, antiepileptic and antidepressant drugs in the pharmacovigilance database from VigiBase

, 2022
Three psychotropic drug classes, benzodiazepines, antiepileptic drugs (AEDs) and antidepressants (ADs), whether used in treatment or overdose, may be associated with respiratory aspiration.
Jose de Leon (4242862), Emilio J. Sanz (13780738), Carlos De Las Cuevas (13780735)   +2 more
core   +1 more source