Results 91 to 100 of about 11,499 (250)

Managing diabetic patients with moderate or severe renal impairment using DPP-4 inhibitors: focus on vildagliptin

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2013
Eleonora Russo, Giuseppe Penno, Stefano Del Prato Department of Clinical and Experimental Medicine, Section of Diabetes and Metabolic Disease, Azienda Ospedaliero Universitaria di Pisa, and University of Pisa, Pisa, Italy Background: Dipeptidyl peptidase-
Russo E, Penno G, Del Prato S
doaj  

Mild acute pancreatitis with vildagliptin use

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Vildagliptin has not been associated with the development of acute pancreatitis in postmarketing reports except one case report from Sydney, Australia.
Ravikant Saraogi   +2 more
doaj   +1 more source

Individualizing treatment targets for elderly patients with type 2 diabetes: factors influencing clinical decision making in the 24-week, randomized INTERVAL study. [PDF]

open access: yes, 2017
ArticleThis is the final version of the article. Available from Impact Journals via the DOI in this record.We tested the feasibility of setting individualized glycemic goals and factors influencing targets set in a clinical trial in elderly patients with
Abhijit, A, Paldanius, PM, Strain, WD
core   +1 more source

Stratified glucose-lowering response to vildagliptin and pioglitazone by obesity and hypertriglyceridemia in a randomized crossover trial [PDF]

open access: gold, 2023
Rebecca Brandon   +19 more
openalex   +1 more source

Pharmacoeconomic analysis of type 2 diabetes mellitus by vildagliptin medication in Kazakhstan [PDF]

open access: yes, 2014
This study is aimed to determine cost-effectiveness of vildagliptin in comparison with sitagliptin for the treatment of patients with type 2 diabetes mellitus (T2DM) from the perspective of Ministry of Health of the Republic of ...
Bektur, C.   +2 more
core  

IRS proteins and diabetic complications [PDF]

open access: yes, 2016
IRS proteins are cellular adaptor molecules that mediate many of the key metabolic actions of insulin. When tyrosine is phosphorylated by the activated insulin receptor, IRS proteins recruit downstream effectors, such as phosphoinositide 3-kinase and ...
Brazil, Derek P.   +2 more
core   +1 more source

Chiral Separation of Vildagliptin by Capillary Electrophoresis—The Study of Enantiomeric Complexation [PDF]

open access: gold, 2023
Lajos Attila Papp   +7 more
openalex   +1 more source

Circulating dipeptidyl peptidase-4 activity is associated with diabetic retinopathy in type 1 diabetic patients [PDF]

open access: yes, 2015
PURPOSE: Diabetic retinopathy (DR) is the most frequent complication among patients with type 1 diabetes mellitus (T1DM). Dipeptidyl peptidase-4 (DPP4) is a protease with elevated activity in patients with T1DM.
Blaslov, Kristina   +2 more
core   +1 more source

Ten Years of Vildagliptin [PDF]

open access: yesEuropean Endocrinology, 2017
After many years of limited therapeutic opportunities, the treatment of type 2 diabetes has become more target and pathophysiologically driven. A typical example is represented by the development of the dipeptidyl peptidase-4 (DPP-4) inhibitors, allowing for more physiological regulation of the endocrine pancreas and leading to a previously unmet risk ...
openaire   +2 more sources

Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling [PDF]

open access: yes, 2017
The Gram-negative anaerobe Porphyromonas gingivalis is associated with chronic periodontitis. Clinical isolates of P. gingivalis strains with high dipeptidyl peptidase 4 (DPP4) expression also had a high capacity for biofilm formation and were more ...
Augustyns, Koen   +11 more
core   +1 more source

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