Results 161 to 170 of about 188,914 (350)

Vimentin‐positive invasive breast carcinoma of no special type: A breast carcinoma with lethal biological characteristics [PDF]

, 2023
Yuki Ichinose, Takahiro Hasebe, Masataka Hirasaki, Ayaka Sakakibara, Hideki Yokogawa, Asami Nukui, Miyuki Hiratsuka, Akihiro Fujimoto, Chihiro Iso, Noriko Wakui, Satomi Shibasaki, Koichi Kamada, Norihiro Suzuki, Yasuo Kamakura, Masanori Yasuda, Asano Aya, Hiroko Shimada, Kazuo Matsuura, Hiroshi Ishiguro, Akihiko Osaki, Toshiaki Saeki   +20 more
openalex   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Additional file 1: of Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis

, 2015
Luisa Lindenberg, Lydia Spengler, Holger Bang, Thomas E. Dorner, Aleksej Maslyanskiy, С. В. Лапин, Е. П. Иливанова, Lorena Martinez‐Gamboa, H. Bastian, Esther Wittenborn, Karl Egerer, G.-R. Burmester, Eugen Feist   +12 more
openalex   +1 more source

Supplemental Figures from Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell–Cancer-Associated Fibroblast Interactions during Collective Invasion

, 2023
Alessandra M. Richardson, Lauren S. Havel, Allyson E. Koyen, Jessica Konen, John W. Shupe, W.G. Wiles, William Martin, Hans E. Grossniklaus, Gabriel Sica, Melissa Gilbert‐Ross, Adam I. Marcus   +10 more
openalex   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Vimentin on the move: new developments in cell migration

, 2018
Rachel A. Battaglia, Samed Delic, Harald Herrmann, Natasha T. Snider   +3 more
openalex   +1 more source

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin [PDF]

, 2012
Ulrike Harre, Dan Georgess, Holger Bang, Aline Bözec, Roland Axmann, Elena Ossipova, Per‐Johan Jakobsson, Wolfgang Baum, Falk Nimmerjahn, Eszter Szarka, Gabriella Sármay, Grit Krumbholz, Elena Neumann, René E. M. Toes, Hans Ulrich Scherer, Anca I. Catrina, Lars Klareskog, Pierre Jurdic, Georg Schett   +18 more
openalex   +1 more source

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

Advanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu, Yan Gao, Yadong Guo, Junfeng Zhang, Wentao Zhang, Zhuoran Gu, Haotian Chen, Chengqi Jin, Peng Luo, Shiyu Mao, Yajuan Hao, Shuo Shi, Xudong Yao   +12 more
wiley   +1 more source

Combination of Vimentin, E-Cadherin, CD44 and CD24 Expression as Predictor Model of Anthracycline Base Neoadjuvant Chemotherapy Response to Stage IIIB Luminal Breast Cancer

, 2018
Bachtiar Budianto, Bambang Pardjianto, Edy Mustofa, Setyawati Soeharto, Solimun Solimun   +4 more
openalex   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source