Results 261 to 270 of about 150,547 (296)

Vimentin at the core of wound healing

Trends in Cell Biology
As a member of the large family of intermediate filaments (IFs), vimentin has emerged as a highly dynamic and versatile cytoskeletal protein involved in many key processes of wound healing. It is well established that vimentin is involved in epithelial-mesenchymal transition (EMT) during wound healing and metastasis, during which epithelial cells ...
John E Eriksson
exaly   +3 more sources

Vimentin antibody production in transplant patients and immunomodulatory effects of vimentin in-vitro

Human Immunology, 2013
We investigated the presence of antibodies to vimentin in 150 patients awaiting transplant, (50 kidney, 50 liver and 50 thoracic) and in 51 previously transplanted kidney patients whose grafts had failed. Patients with primary end stage thoracic or kidney disease did not have increased levels of vimentin antibodies, but those with primary liver failure
Vaughan, Carter, W Martin, Howell
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Vimentin‐positive adenocarcinomas of the stomach: co‐expression of vimentin and cytokeratin

Histopathology, 1996
Recently, the expression of vimentin has been reported in some carcinomas. This study was designed to clarify the significance of vimentin expression in solid type poorly differentiated adenocarcinomas of the stomach. Immunohistochemically, 239 poorly differentiated adenocarcinomas with solid components of the stomach were stained for vimentin ...
T, Utsunomiya, T, Yao, K, Masuda, M, Tsuneyoshi   +3 more
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Desmin and vimentin in regenerating muscles

Muscle & Nerve, 1992
AbstractDesmin is a normal constituent of skeletal muscle fibers; vimentin is contained in myoblasts and connective tissue cells. The intracellular localization of both intermediate filament proteins in regenerating rat muscles was investigated by immunohisto‐ and immunocytochemistry. Necrosis was induced by hot Ringer solution.
Bornemann, A., Schmalbruch, Henning
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Vimentin is secreted by activated macrophages

Nature Cell Biology, 2002
Vimentin is a widely expressed intermediate filament protein thought to be involved mainly in structural processes, such as wound healing. We now demonstrate that activated human macrophages secrete vimentin into the extracellular space. The maturation of blood-derived monocytes into macrophages involves several signalling pathways.
Nirit, Mor-Vaknin, Antonello, Punturieri, Kajal, Sitwala, David M, Markovitz   +3 more
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Role of vimentin in cell migration

Russian Journal of Developmental Biology, 2013
Cell migration plays a crucial role in embryonic development, wound healing, regeneration, inflammation, and immune response, as well as in dissemination of malignant tumors. Vimentin is the marker of migrating cells, but its role in cell migration is still unclear.
I S, Chernoivanenko, An A, Minin, A A, Minin   +2 more
openaire   +2 more sources

Organization and expression of the vimentin gene

Molecular Biology Reports, 1983
The primary structure of hamster vimentin has been derived from the nucleotide sequence of the corresponding cDNA. The elucidation of the amino acid sequence allowed the prediction of a model in which two helix domains occur. The N-terminal and C-terminal part have been characterized as nonhelical domains.
H, Bloemendal, W, Quax, Y, Quax-Jeuken, H, Dodemont, F, Ramaekers, I, Dunia, L, Benedetti   +6 more
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Tetracycline regulated expression of vimentin in fibroblasts derived from vimentin null mice

Journal of Cell Science, 1997
ABSTRACT Fibroblast cell lines were derived from vim−/− mice that express a mouse vimentin transgene in a tetracycline regulatable manner. Vimentin null mouse primary embryo fibroblasts were transformed with SV-40 early genes and vim− cell lines were isolated.
T A, Holwell, S C, Schweitzer, R M, Evans   +2 more
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Mechanics of vimentin intermediate filaments

2003
It is increasingly evident that the cytoskeleton of living cells plays important roles in mechanical and biological functions of the cells. Here we focus on the contribution of intermediate filaments (IFs) to the mechanical behaviors of living cells. Vimentin, a major structural component of IFs in many cell types, is shown to play an important role in
Ning, Wang, Dimitrijie, Stamenovic
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[Expression of vimentin in the lenses of vimentin transgenic mice].

Yan ke xue bao = Eye science, 2004
To observe the expression of vimentin in the lenses of vimentin transgenic mice and investigate the role of vimentin in the formation of cataract.The 12.7 kb chicken vimentin genes were microinjected into the male pronuclei of ICR mice. The injected embryos were transferred to the pseudopregnant recipient females and then generated several transgenic ...
J, Zhou, Y, Hui, Y, Li, P, Zhang, J, Ma
openaire   +1 more source