Results 21 to 30 of about 142,715 (302)

Assessment of Epithelial to Mesenchymal Transition Markers in Breast Carcinoma and its Association with Histopathological Grading, Size and Metastasis [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Carcinoma breast is the most common malignancy affecting women worldwide. Early detection is key to its effective management. Epithelial to Mesenchymal Transition (EMT) has implications in progression of breast carcinoma and metastasis ...
Hage Nobin, Sayeedul Hasan Arif, Afzal Anees , Mohd Khalid   +3 more
doaj   +1 more source

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]

, 2005
Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation.
Erich A. Nigg, Andreas Uldschmid, Hanisch, Anja, Uldschmid, Andreas, Takashi Oguri, Takai, Yasushi, Tomoya Yamaguchi, Yasushi Takai, Masaki Inagaki, Goto, Hidemasa, Tomoya Yokoyama, Anja Hanisch, Hidemasa Goto, Silljé, Herman, Herman Silljé, Oguri, Takashi, Yamaguchi, Tomoya, Nigg, Erich A., Inagaki, Masaki, Yokoyama, Tomoya   +19 more
core   +1 more source

A novel presentation of cutaneous angiosarcoma: A case report and review

Indian Journal of Medical and Paediatric Oncology, 2017
We report a case of a 70-year-old male, with slowly widening induration, ulceration, and oozing for 3 months on the scalp and face. The diagnosis of aggressive cutaneous angiosarcoma was made on histopathology and immunochemistry from the biopsy material
Sonali Bajaj, Prafulla Kumar Sharma, Imroz Singh Sachdev, Minakshi Bhardhwaj   +3 more
doaj   +1 more source

Cytoskeletal protein vimentin interacts with and regulates peroxisome proliferator-activated receptor gamma via a proteasomal degradation process [PDF]

, 2014
Peroxisome proliferators-activated receptor gamma (PPAR) receptor is a transcription factor that is located in and functions primarily in the nucleus.
Tsai, Yun-Chih;Tsai, Shu-Huei;Chang, Emily Yun-Chia;Hee, Siow-Wey;Chen, Wei-Hao;Lee, Sheng-Chung;Chuang, Lee-Ming, 莊立民 ;呂勝春   +1 more
core   +1 more source

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition [PDF]

, 2013
Though clinicians can predict which patients are at risk for developing metastases, traditional therapies often prove ineffective and metastatic disease is the primary cause of cancer patient death; therefore, there is a need to develop anti-metastatic ...
Adam I. Marcus, Songli Xu (457629), Anapatricia Garcia (457628), Paula M. Vertino (457631), Klymkowsky, Michael, Doris R Powell, Marcus Adam I., Vertino, PM, Anapatricia Garcia, Shivendra Singh (457632), Singh Shivendra, Yang, Zhen, Doris R. Powell (457630), Paula M Vertino, Garcia Anapatricia, Vertino Paula M., Singh, Shivendra, Paula M. Vertino, Adam I Marcus, Marcus, Adam I., Garcia, A, Powell, DR, Shivendra Singh, Singh, S, Zhen Yang (107412), Powell, Doris R., Zhen Yang, Yang, Z, Yang Zhen, Vertino, Paula M., Songli Xu, Xu, S, Garcia, Anapatricia, Xu, Songli, Doris R. Powell, Zhen Yang, Adam I. Marcus (457633), Powell Doris R., Marcus, AI, Xu Songli   +39 more
core   +1 more source

Zonula occludens 2 and Cell-Cell Contacts Are Required for Normal Nuclear Shape in Epithelia

Cells, 2021
MAGUK protein ZO-2 is present at tight junctions (TJs) and nuclei. In MDCK ZO-2 knockdown (KD) cells, nuclei exhibit an irregular shape with lobules and indentations.
Christian Hernández-Guzmán, Helios Gallego-Gutiérrez, Bibiana Chávez-Munguía, Dolores Martín-Tapia, Lorenza González-Mariscal   +4 more
doaj   +1 more source

A Small Vimentin-Binding Molecule Blocks Cancer Exosome Release and Reduces Cancer Cell Mobility

Frontiers in Pharmacology, 2021
Vimentin is an intermediate filament protein with diverse roles in health and disease far beyond its structural functions. Exosomes or small extracellular vesicles (sEVs) are key mediators for intercellular communication, contributing to tissue ...
Jianping Wu, Jianping Wu, Qian Xie, Yanjun Liu, Yanan Gao, Zhipeng Qu, Lian Mo, Ying Xu, Ruihuan Chen, Ruihuan Chen, Liyun Shi   +10 more
doaj   +1 more source

Distribution and Clinical Analysis of EpCAM+/Vimentin+ Circulating Tumor Cells in High-Risk Population and Cancer Patients

Frontiers in Oncology, 2021
Circulating Tumor Cells (CTCs) are already present in the peripheral blood of patients with early tumors and even precancerous lesions. The objective of this study was to determine the count of CTCs in peripheral blood from high-risk population(HRP ...
Chunjin Huang, Sheng Ding, Chunyan Huang, Feng Pan, Xiaodong Liu, Haijiao Zhang, Jian Zhou, Xiaofei Liang, Xinyan Wang, Ping Song   +9 more
doaj   +1 more source

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics [PDF]

, 1991
Primary ciliary muscle cell cultures derived from human donors (16-91 years) were established and characterized by comparing them with ciliary muscle in tissue sections using immunocytochemical and ultrastructural methods.
Baur, A., Tamm, Ernst R., Flügel, C., Lütjen-Drecoll, E.   +3 more
core   +1 more source

ROC curve analysis from ELISA results with chimeric fibrin-filaggrin-vimentin-enolase citrullinated peptides (CEFCP, CVECP and CFECP) in the cohort of patients with RA (n = 100) and of blood donors (n = 87). [PDF]

, 2019
ROC curve analysis from ELISA results with chimeric fibrin-filaggrin-vimentin-enolase citrullinated peptides (CEFCP, CVECP and CFECP) in the cohort of patients with RA (n = 100) and of blood donors (n = 87).
Cristina García-Moreno (6659672), Isabel Haro (2148178), Raimon Sanmartí (368935), María José Bleda (6659678), María José Gómara (6659675)   +4 more
core   +1 more source