Results 31 to 40 of about 150,547 (296)

Assessment of Epithelial to Mesenchymal Transition Markers in Breast Carcinoma and its Association with Histopathological Grading, Size and Metastasis [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Carcinoma breast is the most common malignancy affecting women worldwide. Early detection is key to its effective management. Epithelial to Mesenchymal Transition (EMT) has implications in progression of breast carcinoma and metastasis ...
Hage Nobin, Sayeedul Hasan Arif, Afzal Anees , Mohd Khalid   +3 more
doaj   +1 more source

The Hydration of Vimentin

Ophthalmic Research, 2009
The hydration of vimentin isolated from the cortex of bovine lenses was studied by thermal analysis. Differential scanning calorimetry between ––30, and 30°C provided the freezable water content, and thermogravimetric analysis up to 105°C yielded the total water content.
S K, Kakar, F A, Bettelheim
openaire   +2 more sources

A novel presentation of cutaneous angiosarcoma: A case report and review

Indian Journal of Medical and Paediatric Oncology, 2017
We report a case of a 70-year-old male, with slowly widening induration, ulceration, and oozing for 3 months on the scalp and face. The diagnosis of aggressive cutaneous angiosarcoma was made on histopathology and immunochemistry from the biopsy material
Sonali Bajaj, Prafulla Kumar Sharma, Imroz Singh Sachdev, Minakshi Bhardhwaj   +3 more
doaj   +1 more source

Systemic Nanomechanical Single-Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation. [PDF]

Adv Sci (Weinh)
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Ku M, Kwon J, Yoon N, Byeon HK, Yang J.
europepmc   +2 more sources

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition [PDF]

, 2013
Though clinicians can predict which patients are at risk for developing metastases, traditional therapies often prove ineffective and metastatic disease is the primary cause of cancer patient death; therefore, there is a need to develop anti-metastatic ...
Adam I. Marcus, Songli Xu (457629), Anapatricia Garcia (457628), Paula M. Vertino (457631), Klymkowsky, Michael, Doris R Powell, Marcus Adam I., Vertino, PM, Anapatricia Garcia, Shivendra Singh (457632), Singh Shivendra, Yang, Zhen, Doris R. Powell (457630), Paula M Vertino, Garcia Anapatricia, Vertino Paula M., Singh, Shivendra, Paula M. Vertino, Adam I Marcus, Marcus, Adam I., Garcia, A, Powell, DR, Shivendra Singh, Singh, S, Zhen Yang (107412), Powell, Doris R., Zhen Yang, Yang, Z, Yang Zhen, Vertino, Paula M., Songli Xu, Xu, S, Garcia, Anapatricia, Xu, Songli, Doris R. Powell, Zhen Yang, Adam I. Marcus (457633), Powell Doris R., Marcus, AI, Xu Songli   +39 more
core   +2 more sources

Zonula occludens 2 and Cell-Cell Contacts Are Required for Normal Nuclear Shape in Epithelia

Cells, 2021
MAGUK protein ZO-2 is present at tight junctions (TJs) and nuclei. In MDCK ZO-2 knockdown (KD) cells, nuclei exhibit an irregular shape with lobules and indentations.
Christian Hernández-Guzmán, Helios Gallego-Gutiérrez, Bibiana Chávez-Munguía, Dolores Martín-Tapia, Lorenza González-Mariscal   +4 more
doaj   +1 more source

A Small Vimentin-Binding Molecule Blocks Cancer Exosome Release and Reduces Cancer Cell Mobility

Frontiers in Pharmacology, 2021
Vimentin is an intermediate filament protein with diverse roles in health and disease far beyond its structural functions. Exosomes or small extracellular vesicles (sEVs) are key mediators for intercellular communication, contributing to tissue ...
Jianping Wu, Jianping Wu, Qian Xie, Yanjun Liu, Yanan Gao, Zhipeng Qu, Lian Mo, Ying Xu, Ruihuan Chen, Ruihuan Chen, Liyun Shi   +10 more
doaj   +1 more source

Distribution and Clinical Analysis of EpCAM+/Vimentin+ Circulating Tumor Cells in High-Risk Population and Cancer Patients

Frontiers in Oncology, 2021
Circulating Tumor Cells (CTCs) are already present in the peripheral blood of patients with early tumors and even precancerous lesions. The objective of this study was to determine the count of CTCs in peripheral blood from high-risk population(HRP ...
Chunjin Huang, Sheng Ding, Chunyan Huang, Feng Pan, Xiaodong Liu, Haijiao Zhang, Jian Zhou, Xiaofei Liang, Xinyan Wang, Ping Song   +9 more
doaj   +1 more source

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics [PDF]

, 1991
Primary ciliary muscle cell cultures derived from human donors (16-91 years) were established and characterized by comparing them with ciliary muscle in tissue sections using immunocytochemical and ultrastructural methods.
Baur, A., Tamm, Ernst R., Flügel, C., Lütjen-Drecoll, E.   +3 more
core   +1 more source

Dental Tissue and Stem Cells Revisited: New Insights From the Expression of Fibroblast Activation Protein-Alpha

Frontiers in Cell and Developmental Biology, 2020
Fibroblast activation protein-α (FAPα) is a membrane protein with dipeptidyl-peptidase and type I collagenase activity and is expressed during fetal growth.
Ronald B. Driesen, Ronald B. Driesen, Petra Hilkens, Petra Hilkens, Nick Smisdom, Tim Vangansewinkel, Tim Vangansewinkel, Yörg Dillen, Yörg Dillen, Jessica Ratajczak, Jessica Ratajczak, Esther Wolfs, Esther Wolfs, Pascal Gervois, Pascal Gervois, Marcel Ameloot, Annelies Bronckaers, Annelies Bronckaers, Ivo Lambrichts, Ivo Lambrichts   +19 more
doaj   +1 more source