Results 51 to 60 of about 142,715 (302)
Vimentin regulates peripheral nerve myelination [PDF]
, 2012 Myelination is a complex process that requires coordinated Schwann cell-axon interactions during development and regeneration. Positive and negative regulators of myelination have been recently described, and can belong either to Schwann cells or neurons.
Taveggia C +11 more
core +1 more source
Immunohistochemical expression of intermediate filaments in diagnostics of diffuse gliomas.
Medičnì Perspektivi, 2017 Intermediate filament proteins play an important role in maintaining a stable shape, as well as the possible movement of cells, including neoplastic cells.
T. V. Shynkarenko
doaj +1 more source
Murine Colitis is Mediated by Vimentin [PDF]
Scientific Reports, 2013 Vimentin, an abundant intermediate filament protein, presumably has an important role in stabilizing intracellular architecture, but its function is otherwise poorly understood. In a vimentin knockout (Vim KO) mouse model, we note that Vim KO mice challenged with intraperitoneal Escherichia coli control bacterial infection better than do wild-type (WT)
Mor-Vaknin, Nirit +14 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Vimentin increases with disease progression. [PDF]
, 2015 A. In wild-type retinae, vimentin+ve fibers extended throughout the retina at all examined ages (i-vi). Staining at the level of whole retina increased slightly with age (vii). B.
Claire Hippert (171005) +6 more
core +1 more source
Atl directly interacts with host vimentin. [PDF]
, 2022 (A) Pull-down assay of proteins that interact with Atl in STECs. STEC lysates were incubated with His-tagged Atl for 2 h. The final eluted proteins were analyzed by Coomassie Brilliant Blue.
Huixing Lin (4033031) +8 more
core +1 more source
Frontiers in Cardiovascular Medicine, 2022 Vimentin is a type III intermediate filament protein expressed in cells of mesenchymal origin. Vimentin has been thought to function mainly as a structural protein and roles of vimentin in other cellular processes have not been extensively studied.
Seo Yeon Kim +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Vimentin protects differentiating stem cells from stress [PDF]
, 2023 Vimentin is one of the first cytoplasmic intermediate filaments to be expressed in mammalian cells during embryogenesis, but its role in cellular fitness has long been a mystery.
Kaganovich, Daniel +15 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source