Results 51 to 60 of about 150,547 (296)
The structure of the vimentin gene
Cell, 1983 The structure of the chromosomal gene encoding the intermediate filament protein vimentin is described. This gene, which is present as a single copy in the hamster genome, comprises about 10 kb of DNA and contains more than 80% of intron sequences. S1 mapping and sequence analysis reveal nine exons with a total length of 1848 nucleotides.
W, Quax +4 more
openaire +2 more sources
BiologyNovel therapeutic approaches for wound healing have included biomaterials from the Atlantic cod (Gadus morhua L.), with promising results in wound management.
Stefania D’Alessio +3 more
doaj +1 more source
Frontiers in Immunology, 2023 Vimentin is an intermediate filament protein that plays a role in cell processes, including cell migration, cell shape and plasticity, or organelle anchorage.
Jeffrey Arrindell +3 more
doaj +1 more source
陆军军医大学学报, 2023 Objective To investigate the molecular mechanism of focused low-intensity pulsed ultrasound (FLIPUS) to inhibit chondrocyte apoptosis through mechanical effects.
LI Dongqian +3 more
doaj +1 more source
Zaporožskij Medicinskij ŽurnalThe epithelial-mesenchymal transition (EMT) plays a crucial role in the development of pancreatic ductal adenocarcinoma (PDAC). There are insufficient and contradictory data in the scientific literature on the peculiarities of epithelial and mesenchymal ...
M. A. Shyshkin, V. O. Kabachenko
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Oxidation of thiol in the vimentin cytoskeleton [PDF]
Biochemical Journal, 1991 Sublethal doses of H2O2, which induces oxidative stress, cause substantial alteration to the vimentin cytoskeleton in various cell types. We have used a thiol-blot assay to assess thiol status in individual proteins from cell extracts. Vimentin thiol is oxidized in preference to other cytoskeleton proteins.
K R, Rogers, C J, Morris, D R, Blake
openaire +2 more sources
Immunohistochemical expression of intermediate filaments in diagnostics of diffuse gliomas.
Medičnì Perspektivi, 2017 Intermediate filament proteins play an important role in maintaining a stable shape, as well as the possible movement of cells, including neoplastic cells.
T. V. Shynkarenko
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Frontiers in Cardiovascular Medicine, 2022 Vimentin is a type III intermediate filament protein expressed in cells of mesenchymal origin. Vimentin has been thought to function mainly as a structural protein and roles of vimentin in other cellular processes have not been extensively studied.
Seo Yeon Kim +8 more
doaj +1 more source