Results 71 to 80 of about 142,715 (302)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Vimentin associated focal adhesion nanostructure characterization [PDF]
, 2021 Focal adhesions are multiprotein structures that connect cells to the extracellular matrix. They serve as an anchorage site for the cytoskeletal network and play a significant role in mechanosensing and signal transduction, leading to change in cell ...
Aryal, Ujjwal
core
Quantitative study of vimentin gene methylation in stool samples for colorectal cancer screening
Journal of Advanced Pharmaceutical Technology & Research, 2019 Due to importance of screening for colorectal cancer the present study was conducted and aimed at investigating the quantitative methylation of vimentin gene in stool, tumor tissue, and healthy tissue of patients with colorectal cancer (CRC) in ...
Behfar Pakbaz +4 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Immunofluorescence analysis of vimentin expression. [PDF]
, 2013 miR-125b-mimics, inhibitor and NC were transfected into MDA-MB-231 and MCF-7/ADR, respectively. Green, vimentin was immunostained with anti-vimentin; blue, nuclei were stained with DAPI.
Meijuan Zou (320750) +5 more
core +1 more source
Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages
Journal of Innate Immunity, 2019 Pathogenic microorganisms are sensed by the inflammasome, resulting in the release of the pro-immune and proinflammatory cytokine interleukin-1β (IL-1β).
Chih-Ming Tsai +7 more
doaj +1 more source
Analysis of epithelial–mesenchymal transition markers in psoriatic epidermal keratinocytes [PDF]
Open Biology, 2015 Psoriasis is similar to endpoints of epithelial–mesenchymal transition (EMT), a process of epithelial cells transformed into fibroblast-like cells. The molecular epithelial and mesenchymal markers were analysed in psoriatic keratinocytes.
Xiao-Yong Man +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A multifunctional MXene‐integrated GelMA/alginate hydrogel reinforced with TEMPO‐modified nanocellulose is engineered via dynamic covalent, ionic, and hydrogen bonding. The resulting piezoelectric, adhesive, antimicrobial, and 3D‐printable patch enables motion sensing and accelerates wound healing by promoting keratinocyte migration and collagen ...
Myoungjoon Jeon +11 more
wiley +1 more source
Vimentin 3 and endothelin in prostate cancer. [PDF]
, 2018 349 Background: An upregulation of vimentin 3, a truncated version of the full length vimentin, with an unknown function, was previously described by our group, in a direct dependency of increased ET-1 levels.
Melanie von Brandenstein +7 more
core +1 more source
Subcellular Localization of Sprouty2 in Human Glioma Cells
Frontiers in Molecular Neuroscience, 2019 Sprouty proteins act ubiquitously as signaling integrators and inhibitors of receptor tyrosine kinase (RTK) activated pathways. Among the four Sprouty isoforms, Sprouty2 is a key regulator of growth factor signaling in several neurological disorders ...
Barbara Hausott +6 more
doaj +1 more source