Results 71 to 80 of about 150,547 (296)

The ameliorative effect of curcumin on cryptorchid and non-cryptorchid testes in induced unilateral cryptorchidism in albino rat: histological evaluation

open access: yesFolia Morphologica, 2021
BACKGROUND: Cryptorchidism, one or both hidden testes, is the most common abnormality of male sexual development. Subfertility or infertility is associated with both unilateral and bilateral cryptorchidism.
M. A. Abd-El-Hafez   +4 more
doaj   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

open access: yesAdvanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk   +11 more
wiley   +1 more source

Quantitative study of vimentin gene methylation in stool samples for colorectal cancer screening

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2019
Due to importance of screening for colorectal cancer the present study was conducted and aimed at investigating the quantitative methylation of vimentin gene in stool, tumor tissue, and healthy tissue of patients with colorectal cancer (CRC) in ...
Behfar Pakbaz   +4 more
doaj   +1 more source

Computed Tomography‐ and Photoacoustic Imaging‐Active Bioresorbable Electrospun Bismuth Nanoparticle‐Infused Small‐Diameter Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena   +13 more
wiley   +1 more source

Interaction of Vimentin With Actin and Phospholipids

open access: yesThe Biological Bulletin, 1998
Vimentin intermediate filaments are a major cytoskeletal constituent of cells of mesenchymal origin. They have been colocalized with a variety of intracellular structures such as actin filaments and the plasma membrane. Labeled actin filaments, observed in vitro by fluorescence microscopy, break in the presence of polymerizing vimentin; the time course
Shah, J V   +3 more
openaire   +4 more sources

A Direct Interaction between Actin and Vimentin Filaments Mediated by the Tail Domain of Vimentin [PDF]

open access: yesJournal of Biological Chemistry, 2006
The assembly and organization of the three major eukaryotic cytoskeleton proteins, actin, microtubules, and intermediate filaments, are highly interdependent. Through evolution, cells have developed specialized multifunctional proteins that mediate the cross-linking of these cytoskeleton filament networks.
Osigwe, Esue   +3 more
openaire   +2 more sources

Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages

open access: yesJournal of Innate Immunity, 2019
Pathogenic microorganisms are sensed by the inflammasome, resulting in the release of the pro-immune and proinflammatory cytokine interleukin-1β (IL-1β).
Chih-Ming Tsai   +7 more
doaj   +1 more source

Analysis of epithelial–mesenchymal transition markers in psoriatic epidermal keratinocytes [PDF]

open access: yesOpen Biology, 2015
Psoriasis is similar to endpoints of epithelial–mesenchymal transition (EMT), a process of epithelial cells transformed into fibroblast-like cells. The molecular epithelial and mesenchymal markers were analysed in psoriatic keratinocytes.
Xiao-Yong Man   +8 more
doaj   +1 more source

Vimentin mediates uptake of C3 exoenzyme. [PDF]

open access: yes, 2014
Clostridium botulinum C3 exoenzyme (C3) selectively inactivates RhoA/B/C GTPases by ADP-ribosylation. Based on this substrate specificity C3 is a well-established tool in cell biology.
Andreas Pich   +13 more
core   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

open access: yesAdvanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz   +5 more
wiley   +1 more source

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