Results 81 to 90 of about 150,547 (296)

Subcellular Localization of Sprouty2 in Human Glioma Cells

Frontiers in Molecular Neuroscience, 2019
Sprouty proteins act ubiquitously as signaling integrators and inhibitors of receptor tyrosine kinase (RTK) activated pathways. Among the four Sprouty isoforms, Sprouty2 is a key regulator of growth factor signaling in several neurological disorders ...
Barbara Hausott, Jong-Whi Park, Taras Valovka, Martin Offterdinger, Michael W. Hess, Stephan Geley, Lars Klimaschewski   +6 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Alveolar rhabdomyosarcoma in a dog confirmed using myogenin immunohistochemistry: a case report

Veterinární Medicína, 2016
A large mass from the right forelimb of a five-year-old, male, Maltese dog, was resected surgically and examined histopathologically. Grossly, the 4 × 6 cm mass was well-demarcated and firm.
J.K. Park, E.M. Lee, A.Y. Kim, E.J. Lee, I.H. Hong, M.R. Ki, K.S. Jeong   +6 more
doaj   +1 more source

Analysis of vimentin phosphorylation involved in vimentin rearrangement during EV71 infection.

, 2013
(A) Confocal microscopy analysis of vimentin phosphorylation in U251 cells infected with EV71 showing only ser 82-p vimentin colocalized with aggresomes. At 24 h postinfection cells were stained with antibodies specific to either Ser-55-, Ser-33-, Ser-38-
Zhang Wenliang (461432), Ning Du (367178), Cong Haolong (461429), Tien Po (461434), Zhang Hua (461431), Song Lei (461433), Zhang Wei (317854), Tian Hongchao (461430), Yang Yang (45629)   +8 more
core   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

Spindle cell lipoma in the gingiva of a dog: a case report

Veterinární Medicína, 2015
Spindle cell lipoma is a benign lipomatous tumour that mainly occurs in the subcutis of the head, neck, and shoulder in elderly men. Oral spindle cell lipoma is extremely rare in all species, and no cases have been reported in veterinary medicine.
H.J. Kim, E.J. Choi, H.R. Lee, G.J. Park, E.S. Yun, J.H. Kim, S.H. Do   +6 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

MOMAST^® Downregulates AQP3 Expression and Function in Human Colon Cells

Antioxidants
The water channel AQP3 is an aquaglyceroporin expressed in villus epithelial cells, and it plays a role in water transport across human colonic surface cells. Beyond water, AQP3 can mediate glycerol and H2O2 transport. Abnormal expression and function of
Ines Angelini, Mariangela Centrone, Giusy Rita Caponio, Annarita Di Mise, Andrea Gerbino, Marianna Ranieri, Giovanna Valenti, Grazia Tamma   +7 more
doaj   +1 more source

Diagnostic approach to malignant fibrous histiocytomas of soft tissue in dogs: a case report

Veterinární Medicína, 2013
Malignant fibrous histiocytomas (MFHs), newly named as 'undifferentiated pleomorphic sarcomas' in 2002 by the World Health Organization, generally show an ambiguous origin.
J.S. Ko, H.J. Kim, Y.M. Choi, J.W. Kim, C. Park, S.H. Do   +5 more
doaj   +1 more source

Vimentin regulates peripheral nerve myelination

, 2012
Myelination is a complex process that requires coordinated Schwann cell-axon interactions during development and regeneration. Positive and negative regulators of myelination have been recently described, and can belong either to Schwann cells or neurons.
Taveggia C, Vaccari I, Domi T, Previtali SC, Porrello E, Quattrini A, Dina G, Rivellini C, Cerri F, Bolino A, Triolo D, La Marca R   +11 more
core   +1 more source