Results 101 to 110 of about 150,547 (296)
Undervalued ubiquitous proteins
4 open, 2019 The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
Vimentin increases with disease progression.
, 2015 A. In wild-type retinae, vimentin+ve fibers extended throughout the retina at all examined ages (i-vi). Staining at the level of whole retina increased slightly with age (vii). B.
Claire Hippert (171005) +6 more
core +1 more source
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Advanced Science, EarlyView.Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, EarlyView.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Vimentin regulates mitochondrial ROS production and inflammatory responses of neutrophils
Frontiers in ImmunologyThe intermediate filament vimentin is present in immune cells and is implicated in proinflammatory immune responses. Whether and how it supports antimicrobial activities of neutrophils are not well established.
Thao Ngoc Huynh +9 more
doaj +1 more source
Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes
Cells, 2019 Vimentin (VIM) is an intermediate filament (nanofilament) protein expressed in multiple cell types, including astrocytes. Mice with VIM mutations of serine sites phosphorylated during mitosis (VIMSA/SA) show cytokinetic failure in fibroblasts and lens ...
Yolanda de Pablo +6 more
doaj +1 more source
Advanced Science, EarlyView.This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source
Vimentin associated focal adhesion nanostructure characterization
, 2021 Focal adhesions are multiprotein structures that connect cells to the extracellular matrix. They serve as an anchorage site for the cytoskeletal network and play a significant role in mechanosensing and signal transduction, leading to change in cell ...
Aryal, Ujjwal
core +1 more source
The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells [PDF]
, 2019 CITATION: Kaschula, C. H., et al. 2019. The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells.
Hunter, Roger +29 more
core +1 more source
Atl directly interacts with host vimentin.
, 2022 (A) Pull-down assay of proteins that interact with Atl in STECs. STEC lysates were incubated with His-tagged Atl for 2 h. The final eluted proteins were analyzed by Coomassie Brilliant Blue.
Huixing Lin (4033031) +8 more
core +1 more source