Professional Perspectives on Children's Participation in the Chilean Child Protection System
Child &Family Social Work, EarlyView.ABSTRACT Meaningful participation in child protection systems is crucial for enhancing both decision‐making processes and the lives of children and adolescents. This study explores professionals' perceptions of child participation and risk assessment within the Chilean Child Protection System.
Manuela García‐Quiroga +2 more
wiley +1 more source
FLOWR: flow matching for structure-aware de novo, interaction- and fragment-based ligand generation. [PDF]
Nat Comput SciCremer J +5 more
europepmc +1 more source
Sleep Medicine Education in Italian Undergraduate and Post‐Graduate Dental Programs
European Journal of Dental Education, EarlyView.ABSTRACT Introduction Sleep‐related breathing disorders (SRBD), particularly obstructive sleep apnea (OSA), represent a major public health concern, yet remain widely underdiagnosed. Dentists play an important role in screening, referral, and management of SRBD; however, the extent of sleep medicine education in Italian dental curricula is unknown ...
Federica Guglielmi +5 more
wiley +1 more source
Assessing the factors influencing the quality of pocket-conditioned 3D generative models. [PDF]
J CheminformWang K +4 more
europepmc +1 more source
Attitudes of Dental Students Towards HIV+ Patients: A Multi‐Center Survey Among Italian Universities
European Journal of Dental Education, EarlyView.ABSTRACT Aims To evaluate the attitudes of Italian dental students towards HIV‐infected patients and explore factors influencing discriminatory behaviour. Methods This observational, multicentric survey analysed responses from dental students across Italian Dental Schools.
Michele Giuliani +55 more
wiley +1 more source
PL-PatchSurfer3: improved structure-based virtual screening for structure variation using 3D Zernike descriptors. [PDF]
J CheminformShin WH, Kagaya Y, Jang W, Kihara D.
europepmc +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
Probe-Atom Distributions Obtained from Mixed-Solvent Molecular Dynamics Improve the Scoring of Docking Calculations. [PDF]
J Chem Inf ModelAkaki K, Yanagisawa K, Akiyama Y.
europepmc +1 more source
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Comparative Structure-Based Analysis of Predicted BZD9L1 Binding Modes Across Human Sirtuins. [PDF]
Int J Mol SciTan YJ, Lee YT, Oon CE, Mancera RL.
europepmc +1 more source