Results 111 to 120 of about 3,771 (159)

The insensitivity of Vinca rosea to vinblastine

Chromosoma, 1977
Root tip mitosis in both Vinca rosea and the chosen control Lepidium sativum is susceptible to the effects of colchicine at and above 5X10(-4)M.--Root tip mitosis in L. sativum is susceptible to the effects of vinblastine at concentrations equal to and greater than 10(-4)M, while root tip mitosis in V.
M R, Kramers, H, Stebbings
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In vitro synthesis of spermidine in the higher plant, Vinca rosea

Biochemical and Biophysical Research Communications, 1973
Cell-free extracts of Vinca rosea seedlings exhibited enzyme activities for the following reactions: S-adenosyl-L-methionine (SAM) decarboxylation, spermidine synthesis from decarboxylated SAM and putrescine, and 5′-methylthioadenosine hydrolysis to 5-S-methyl-5-thio-D-ribose and adenine.
C, Baxter, C J, Coscia
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Assay Methods for Some Vinca rosea Alkaloids II

Journal of Pharmaceutical Sciences, 1964
Colorimetric and fluorometric methods are presented for quantitative determination of some Vinca alkaloids. The identification is accomplished with a new color reagent—ceric ammonium sulfate in phosphoric acid—and two thin-layer chromatographic systems.
I M, JAKOVLJEVIC, L D, SEAY, R W, SHAFFER   +2 more
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New Derivatives of the Vinca Rosea Alkaloids

Acta geneticae medicae et gemellologiae, 1968
Summary1. Vinblastine (VLB) and vincristine (VCR) are both naturally occurring alkaloids derived from the flowering periwinkle plant, Vinca rosea, Linn.2. Both drugs have large molecules and are very similar in chemical structure. They differ only in that VLB has a methyl group (-CH3) while VCR has a formyl group (-CHO) attached to one of the nitrogen ...
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Hydroxylation of geraniol and nerol by a monooxygenase from Vinca rosea

Biochemical and Biophysical Research Communications, 1973
Abstract A microsomal mixed function oxidase isolated from V. rosea seedlings was shown to catalyze the hydroxylation of the monoterpene alcohols, geraniol and nerol, to their corresponding 10-hydroxy derivatives. Hydroxylase activity was dependent upon NADPH and oxygen and was associated with the 100,000 X g pellet which exhibited a characteristic
T D, Meehan, C J, Coscia
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Roseoside-A C13 glycoside from Vinca Rosea

Phytochemistry, 1974
Abstract Roseoside, a C13 glycoside isolated from Vinca rosea has been assigned the structure and stereochemistry (1).
D.S. Bhakuni, P.P. Joshi, Hema Uprety, R.S. Kapil   +3 more
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Isolation of Reserpine from Vinca rosea Linn.

Nature, 1958
IN recent years considerable interest has been aroused in the use of the alkaloid reserpine in the treatment of hypertension and various mental disorders. Various plants in the family of Apocynaceae other than Rauwolfia have been investigated, and among them the isolation of reserpine from Alstonia constricta 1 is noteworthy. With the view of detecting
N K, BASU, B, SARKAR
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Octopine dehydrogenase of a vinca rosea crown gall tumor

Phytochemistry, 1983
Abstract Octopine dehydrogenase (ODH) (EC 1.5.1.11) from crown gall tumor tissue induced by Agrobacterium tumefaciens strain W1 on Vinca rosea was purified 300-fold, yielding a single active enzyme with a MW of 38 000. The enzyme shows activity with four α-ketoacids and 16 amino acids.
Paul R. Birnberg, Sukanya S. Rao, James A. Lippincott   +2 more
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Erythrocytes and "vinca rosea" alkaloids. An in vitro study.

Nouvelle revue francaise d'hematologie, 1980
The reported stereoscan images have proved that overtherapeutic amounts of vincristine induce in normal red cells the same effects as vinblastine, i.e. the onset of spherocytosis (in about 30% of the cells) and spherostomatocytosis (in the remainder) associated with distinct smaller vacuoles surrounding the larger cavity.
ZAVAGLI, Giorgio, RICCI, Giorgio, LOGALLO G.   +2 more
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Observations on the administration of iridodial-7-14C to vinca rosea

Phytochemistry, 1969
Abstract It has been suggested that iridodial is a biosynthetic intermediate between geraniol and loganin, which is a precursor of the non-tryptophan derived portion of vindoline, catharanthine, ajmalicine, and other indole alkaloids found in Vinca rosea . Iridodial-7- 14 C was synthesized from ethyl iodide-1- 14 C and fed to V.
Robert M. Bowman, Edward Leete
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