Results 11 to 20 of about 70,411 (245)

Successful Management of Visceral Kaposiform Hemangioendothelioma with Kasabach‐Merritt Phenomenon Using Corticosteroids and Vincristine [PDF]

Neonatal Medicine, 2020
Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular neoplasm that often develops a coagulopathy known as Kasabach­Merritt phenomenon (KMP). Visceral involvement denotes a poor prognosis.
Mi Hyeon Gang, Yeon Jung Lim, Mea-young Chang   +2 more
doaj   +1 more source

The pharmacogenomics of vincristine-induced peripheral neuropathy in pediatric acute lymphoblastic leukemia patients in Serbia - a single center experience [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2022
Introduction/Objective. Vincristine (VCR) is one of the key drugs in current treatment protocols for pediatric acute lymphoblastic leukemia (ALL). By destabilizing microtubules, VCR arrests cells in metaphase, inducing apoptosis of malignant cells.
Ristivojević Bojan, Kotur Nikola, Stanković Biljana, Gašić Vladimir, Lazić Jelena, Pavlović Sonja, Zukić Branka   +6 more
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Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain

Frontiers in Pharmacology, 2021
Gastrodin (GAS) is the main bioactive ingredient of Gastrodia, a famous Chinese herbal medicine widely used as an analgesic, but the underlying analgesic mechanism is still unclear.
Xiangyu Wang, Boxuan Zhang, Xuedong Li, Xuedong Li, Xingang Liu, Songsong Wang, Yuan Xie, Jialing Pi, Zhiyuan Yang, Jincan Li, Qingzhong Jia, Qingzhong Jia, Qingzhong Jia, Qingzhong Jia, Yang Zhang, Yang Zhang   +15 more
doaj   +1 more source

Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk Factor

Frontiers in Pharmacology, 2021
Vincristine (VCR) is the first-line chemotherapeutic medication often co-administered with other drugs to treat childhood acute lymphoblastic leukemia. Dose-dependent neurotoxicity is the main factor restricting VCR’s clinical application.
Qing-Yan Yang, Qing-Yan Yang, Ya-Hui Hu, Hong-Li Guo, Ying Xia, Yong Zhang, Wei-Rong Fang, Yun-Man Li, Jing Xu, Feng Chen, Yong-Ren Wang, Teng-Fei Wang   +11 more
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Recurrent vincristine‐associated fever in a child with Wilms tumor

Cancer Reports, 2022
Background Fever is a common complaint among children with an underlying oncologic diagnosis, especially during chemotherapy courses and periods of neutropenia.
Eman T. Al‐Antary, Sarah Ramiz
doaj   +1 more source

Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways

Frontiers in Pharmacology, 2022
Background: Vincristine (VCR) is used in the clinic as an anti-tumor drug. VCR can cause pulmonary fibrosis (PF), leading to respiratory failure. The transformation of fibroblasts into myofibroblasts may play a key role in PF. The present study attempted
Hui Xu, Jingwen Yang, Mengyun Tu, Jie Weng, Mengying Xie, Zhiliang Zhou, Peisen Zhou, Liang Wang, Chan Chen, Chan Chen, Zhiyi Wang, Zhiyi Wang   +11 more
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Lipid peroxidation in rats treated with vincristine sulphate and nandrolone decanoate

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011
Brain and serum lipid peroxidation was studied in rats treated with vincristine sulphate and different doses of nandrolone decanoate. Thirty rats were distributed into six groups (n=5). The treatments were applied once a week for two weeks.
D.B Martins, S.T.A Lopes, C.M Mazzanti, R Spanevello, R Schmatz, M Corrêa, N Stefanello, M.R Schetinger, V Morsch, A.P.M Veiga   +9 more
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Prognosis and complete remission rate of diffuse large B‐cell lymphoma patients in standard R‐CHOP with reduction of vincristine: A retrospective study

Health Science Reports, 2023
Background and Aims The effect of stopping or reducing the dose of vincristine in diffuse large B‐cell lymphoma (DLBCL) on the outcome and prognosis of the disease is still in doubt.
Fatemeh Riasi, Sajjad Ataei Azimi, Abolghasem Allahyari, Mohammad Moeini Nodeh, Mohammad T. Shakeri, Mostafa Kamandi   +5 more
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The Effect of Vincristine on Hypoxic, Apoptotic, and Autophagic Gene Expressions in Gastric Cancer Cells under Hypoxic Conditions [PDF]

Middle East Journal of Cancer, 2023
Background: Apoptosis and autophagy functions are known as death-inducing mechanisms. Vincristine (VCR) is a chemotherapeutic drug that binds with tubulin dimers and induces apoptosis in cancer cells. Furthermore, VCR protects cancer cells from apoptosis,
Meliha Irmak-Yazicioglu, Betül Ceylaner
doaj   +1 more source

Intratumoral recombinant human interferon alpha‐2a and vincristine combination therapy in canine transmissible venereal tumour

Veterinary Medicine and Science, 2018
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the ...
Halit Kanca, Gizem Tez, Kazim Bal, Dogukan Ozen, Eray Alcigir, Sevil Atalay Vural   +5 more
doaj   +1 more source