Results 21 to 30 of about 71,512 (251)
CD24 blunts the sensitivity of retinoblastoma to vincristine by modulating autophagy
Molecular Oncology, 2020 Retinoblastoma (RB) is the most common childhood malignant intraocular tumor. The clinical efficacy of vincristine (VCR) in the treatment of RB is severely limited by drug resistance. Here, we found that CD24, a GPI‐anchored protein, was overexpressed in
Jie Sun +7 more
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Effects of cromolyn sodium and honey on vincristine-induced neuropathic pain: An experimental study in mice [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریزBackground. Chemotherapy-induced neuropathy is a significant side effect of anticancer drugs such as vincristine, leading to increased pain sensitivity and reduced quality of life. Investigations are required to reduce these adverse effects.
Moslem Najafi +3 more
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Molecules, 2022 Chemotherapeutic agent-induced nausea and vomiting are the severe adverse effects that are induced by their stimulations on the peripheral and/or central emetic nerve pathways. Even though ginger has been widely used as an herbal medicine to treat emesis,
Mayur J. Patil +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
Revisiting the management of chronic ITP; a randomized controlled clinical trial
Platelets, 2021 The balance between therapy effectiveness and economic efficiency in chronic immune thrombocytopenia (ITP) becomes more confusing. This single-center open label randomized controlled trial evaluates the effectiveness and safety of hydroxychloroquine in ...
Ghada E. M. Abdallah +5 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Drug Delivery, 2017 Therapeutic outcome for the treatment of glioma was often limited due to drug resistance and low permeability of drug across the multiple physiological barriers, including the blood-brain barrier (BBB), and the blood-tumor barrier (BTB).
Yue Zhang +10 more
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Scientific ReportsPeripheral neurotoxicity is a dose-limiting adverse reaction of primary frontline chemotherapeutic agents, including vincristine. Neuropathy can be so disabling that patients drop out of potentially curative therapy, negatively impacting cancer prognosis.
Irina Utkina-Sosunova +15 more
doaj +1 more source
Primary bladder lymphoma, diffuse large B-cell type: Case report and literature review of 26 cases
Urology Annals, 2015 Primary lymphoma of the urinary bladder is exceedingly rare, representing 0.2% of all extranodal non-Hodgkin′s lymphoma. Although Matsuno et al. and others state the most common type is mucosa-associated lymphoid tissue (MALT) lymphoma, 20% of all the ...
W Greg Simpson +3 more
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