Results 21 to 30 of about 111,805 (253)

Lipid peroxidation in rats treated with vincristine sulphate and nandrolone decanoate

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011
Brain and serum lipid peroxidation was studied in rats treated with vincristine sulphate and different doses of nandrolone decanoate. Thirty rats were distributed into six groups (n=5). The treatments were applied once a week for two weeks.
D.B Martins   +9 more
doaj   +1 more source

Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf. [PDF]

open access: yes, 2010
U radu je opisana izolacija pet sastojaka petroleterske i diklormetanske frakcije metanolnog ekstrakta kore biljke Delonix regia: lupeol (1), epilupeol (2), β-sitosterol (3), stigmasterol (4) i p-metoksibenzaldehid (5). Nadalje, testirano je antimikrobno
A. Bauer   +18 more
core   +3 more sources

Vincristine-induced peripheral neuropathic pain and expression of transient receptor potential vanilloid 1 in rat

open access: yesJournal of Pharmacological Sciences, 2017
The clinical anti-cancer efficacy of vincristine is limited by the development of dose-dependent peripheral neuropathy. Up-regulation of transient receptor potential vanilloid 1 (TRPV1) is correlated with peripheral neuropathy following anti-cancer drug ...
Terumasa Chiba   +6 more
doaj   +1 more source

Prognosis and complete remission rate of diffuse large B‐cell lymphoma patients in standard R‐CHOP with reduction of vincristine: A retrospective study

open access: yesHealth Science Reports, 2023
Background and Aims The effect of stopping or reducing the dose of vincristine in diffuse large B‐cell lymphoma (DLBCL) on the outcome and prognosis of the disease is still in doubt.
Fatemeh Riasi   +5 more
doaj   +1 more source

The Effect of Vincristine on Hypoxic, Apoptotic, and Autophagic Gene Expressions in Gastric Cancer Cells under Hypoxic Conditions [PDF]

open access: yesMiddle East Journal of Cancer, 2023
Background: Apoptosis and autophagy functions are known as death-inducing mechanisms. Vincristine (VCR) is a chemotherapeutic drug that binds with tubulin dimers and induces apoptosis in cancer cells. Furthermore, VCR protects cancer cells from apoptosis,
Meliha Irmak-Yazicioglu, Betül Ceylaner
doaj   +1 more source

Intratumoral recombinant human interferon alpha‐2a and vincristine combination therapy in canine transmissible venereal tumour

open access: yesVeterinary Medicine and Science, 2018
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the ...
Halit Kanca   +5 more
doaj   +1 more source

CD24 blunts the sensitivity of retinoblastoma to vincristine by modulating autophagy

open access: yesMolecular Oncology, 2020
Retinoblastoma (RB) is the most common childhood malignant intraocular tumor. The clinical efficacy of vincristine (VCR) in the treatment of RB is severely limited by drug resistance. Here, we found that CD24, a GPI‐anchored protein, was overexpressed in
Jie Sun   +7 more
doaj   +1 more source

A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response [PDF]

open access: yes, 2019
The ImbruVeRCHOP trial is an investigator-initiated, multicenter, single-arm, open label Phase I/II study for patients 61-80 years of age with newly diagnosed CD20+ diffuse large B-cell lymphoma and a higher risk profile (International Prognostic Index ...
Anagnostopoulos, Ioannis   +7 more
core   +2 more sources

Is now the time for molecular driven therapy for diffuse large B-cell lymphoma? [PDF]

open access: yes, 2017
INTRODUCTION: Recent genetic and molecular discoveries regarding alterations in diffuse large B-cell lymphoma (DLBCL) deeply changed the approach to this lymphoproliferative disorder.
Ansuinelli, Michela   +4 more
core   +1 more source

Effects of cromolyn sodium and honey on vincristine-induced neuropathic pain: An experimental study in mice [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Chemotherapy-induced neuropathy is a significant side effect of anticancer drugs such as vincristine, leading to increased pain sensitivity and reduced quality of life. Investigations are required to reduce these adverse effects.
Moslem Najafi   +3 more
doaj   +1 more source

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