Results 81 to 90 of about 2,154 (205)

Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design [PDF]

, 2009
Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new
Keserű, György Miklós, Menyhárd, D.K., Náray-Szabó, Gábor   +2 more
core  

Plant cell culture technology in the cosmetics and food industries : current state and future trends [PDF]

, 2018
The production of drugs, cosmetics, and food which are derived from plant cell and tissue cultures has a long tradition. The emerging trend of manufacturing cosmetics and food products in a natural and sustainable manner has brought a new wave in plant ...
A Barbulova, A Carola, A Fehér, A Singh, A Stafford, A Tassoni, A Tito, A Tito, AM Nosov, AR Stiles, B Fonseca-Santos, B Ruffoni, BM Schmidt, BW Yun, C Curtin, C Schürch, C Zappelli, CS Mattick, D Hess, D Lijavetzky, D Schmid, D Schmid, David Schildberger, DE Evans, Dieter Eibl, E Belser, E Nordlund, E Ritterhaus, EF George, EK Lee, F Apone, F Sato, FR Quiroz-Figueroa, G Haberlandt, G Ravishankar, G Sivakumar, H Deno, H Gutzeit, H Sood, H Tanaka, HM Schumacher, HN Murthy, HN Murthy, HR Jang, I Stutz, Irène Stutz, J Reynolds, J Steingroewer, J Steingroewer, J Suvanto, J Wu, JP Ducos, JP Ducos, K Hibino, KM Davies, KY Paek, KY Paek, L Fei, L Nohynek, L Pistelli, M Bimonte, M Goel, M Morus, M Ochoa-Villarreal, M Tschofen, Md. Mohidul Hasan, MI Georgiev, MI Georgiev, MI Georgiev, MS Hussain, N Lehmann, N Räty, N Sevón, NHA Mamun, Nico M.G. Oosterhuis, O Martino Di, OL Gamborg, P Jeandet, P Sharma, P Sharma, P Weathers, P Zhou, Philipp Meier, PJ Weathers, PM Naik, R Dal Toso, R Dal Toso, R Dal Toso, R Eibl, R Eibl, Regine Eibl, RU Schenk, S Chattopadhyay, S Cuperus, S Trehan, S Werner, S Werner, S Werner, S Werner, SH Moon, SS Bhojwani, T Greb, T Murashige, Tilo Hühn, TJ Fu, V Georgiev, V Georgiev, VIP Loake, WRL Curtis, YJ Jiang   +109 more
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A phase II, multicentre, UK study of vinorelbine in advanced breast cancer. [PDF]

, 2016
Clinical Trial, Phase IIMulticenter StudyFull text is available as a scanned copy of the original print versionThirty-four evaluable patients were treated with vinorelbine, a novel, semisynthetic vinca alkaloid, as first-line chemotherapy for advanced ...
Canney, P, Coleman, RE, Curnow, Alison, Dobbs, NA, Rubens, RD, Stewart, AL, Twelves, CJ, Tyrrell, CJ   +7 more
core  

Artemisinic Acid Serves as a Novel Inducer to Enhance Biosynthesis of Terpenoid Indole Alkaloids in Cambial Meristematic Cells

Natural Product Communications, 2016
To investigate the effect of artemisinic acid (AA) on improving the production of terpenoid indole alkaloids (TIAs) of Catharanthus roseus cambial meristematic cells (CMCs), feeding AA to C.
Mingxuan Wang, Jiachen Zi, Jianhua Zhu, Shan Chen, Pu Wang, Liyan Song, Rongmin Yu   +6 more
doaj   +1 more source

Binary Stress Induces an Increase in Indole Alkaloid Biosynthesis in Catharanthus roseus

Frontiers in Plant Science, 2015
Catharanthus roseus is an important medicinal plant, which produces a variety of indole alkaloids of significant pharmaceutical relevance. In the present study, we aimed to investigate the potential stress-induced increase of indole alkaloid biosynthesis
Wei eZhu, Bingxian eYang, Setsuko eKomatsu, Xiaoping eLu, Ximin eLi, Jingkui eTian   +5 more
doaj   +1 more source

Exploring the production of high-value compounds in plant Catharanthus roseus hairy roots and yeast Yarrowia lipolytica [PDF]

, 2017
This dissertation focuses on studying the production of two categories of high-value compounds in bio organisms. The first group is terpenoid indole alkaloids (TIAs) in plant Catharanthus roseus, and the second group is wax esters, one of fatty acid ...
Zhao, Le
core   +3 more sources

Cytological changes in meristematic cells of Allium cepa L. root tip treated with extracts from callus of Catharanthus roseus (L.) G. Don

Acta Societatis Botanicorum Poloniae, 2014
The effect of an ethanolic extract from callus of Catharanthus roseus on Allium cepa root cells divisions was investigated. Two lines: white and green callus, were established on solid B5 medium with IAA 1 mg/l and kinetin 0.1 mg/l.
Agnieszka Pietrosiuk, Mirosława Furmanowa, Alicja Zobel, Mieczysław Kuraś, Agnieszka Michalak   +4 more
doaj   +1 more source

A Novel AP2/ERF Transcription Factor CR1 Regulates the Accumulation of Vindoline and Serpentine in Catharanthus roseus

Frontiers in Plant Science, 2017
As one type of the most important alkaloids in the world, terpenoid indole alkaloids (TIAs) show a wide range of pharmaceutical activities that are beneficial for clinical treatments.
Jiaqi Liu, Fangyuan Gao, Juansheng Ren, Xianjun Lu, Guangjun Ren, Rui Wang   +5 more
doaj   +1 more source

A Simplified Procedure for Indole Alkaloid Extraction from Catharanthus roseus Combined with a Semi-synthetic Production Process for Vinblastine

Molecules, 2007
Dried leaves of Catharanthus roseus were extracted with aqueous acidic 0.1 M solution of HCl. Alkaloid-embonate complexes were obtained as precipitates by treating the extract with an alkaline (NaOH) solution of embonic acid (4,4-methylene-bis-3 ...
Marja-Liisa Riekkola, Aarre Huhtikangas, Tuulikki Seppänen-Laakso, Into Laakso, Arvind Verma   +4 more
doaj   +1 more source

Cyclopropanation of Some Alkaloids [PDF]

, 2015
New derivatives of natural compounds, galanthamine using in treatment of  Alzheimer’s disease and antitumor dimer alkaloids vinblastine and vincristine were synthesized.
Hazai, László, Kalaus, György, Keglevich, Péter, Szántay, Csaba   +3 more
core   +2 more sources