Results 31 to 40 of about 1,667 (200)
Vinpocetine for acute ischaemic stroke [PDF]
Stroke, 1997 Vasoactive and neuroprotective drugs are used to treat stroke in some countries.The objective of this review was to assess the effect of vinpocetine in acute ischaemic stroke.We searched the Cochrane Stroke Group trials register (last searched: August 1999) and Medline.
D, Bereczki, I, Fekete
openaire +4 more sources
PEG- 4000 increases solubility and dissolution rate of vinpocetin in solid dispersion system
Chimica Techno Acta, 2022 In the present work investigations were performed concerned with the determination of the optimal ratio of vinpocetine and polyethylene glycol within a solid dispersion (1:2 or 1:5) according to the simulation results in the framework of molecular ...
Yulia A. Polkovnikova +3 more
doaj +1 more source
Comparative study of the specific activity of soft application drugs with vinpocetine
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022 In modern neurology, the main component of successful treatment of cerebrovascular pathology is pharmacotherapy. At the same time, the arsenal of effective medicines of evidence-based medicine in this area is quite limited.
V. V. Hladyshev +6 more
doaj +1 more source
Journal of Pharmacological Sciences, 2021 The progressive degeneration of the excitable cells of the ear depends on the sustained excitation of the voltage-sensitive sodium channels, so the negative pharmacological modulation could be a rational therapeutic strategy against the damage of these ...
Ileana Gutiérrez-Farfán +5 more
doaj +1 more source
Synthesis and pharmacological activity of vinpocetine derivatives. [PDF]
RSC AdvVinpocetine and Vincamine were extensively employed in the treatment of ischemic stroke, serving as effective cerebrovascular vasodilators.
Dong ZC +5 more
europepmc +3 more sources
Vinpocetine and Ischemic Stroke
, 2021 Vinpocetine (VPN) is a synthetic ethyl-ester derivative of the alkaloid apovincamine from Vinca minor leaves. VPN is a selective inhibitor of phosphodiesterase type 1 (PDE1) has potential neurological effects through inhibition of voltage gated sodium channel and reduction of neuronal calcium influx.
Hayder M. Al-kuraishy, Ali I. Al-Gareeb
openaire +2 more sources
Effectiveness and Safety of Ginkgo biloba, Vinpocetine and Piracetam as a Single Agent and Fixed Dose Combination in Patients with Subjective Tinnitus [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Owing to the lack of any standard treatment, subjective tinnitus can be debilitating, manifesting a varied population response to tinnitus management.
Paul Mathai, Anu Chandran, Sourav Das
doaj +1 more source
Vinpocetine improves oxidative stress and pro-inflammatory mediators in acute kidney injury
International Journal of Preventive Medicine, 2019 Background: Gentamicin-induced-acute kidney injury (AKI) is a multifaceted phenomenon which previously linked to the oxidative stress only. Vinpocetine prevents reactive free radical generation which contributed in reduction of damage.
Hayder M Al-Kuraishy +2 more
doaj +1 more source
Cognitive impairment in COVID-19: associations, pathogenesis and treatment questions
Неврология, нейропсихиатрия, психосоматика, 2021 Cognitive impairment (CI) can be neurological symptoms or complications of coronavirus disease 2019 (COVID-19). Among the pathogenetic mechanisms, the neurotropicity of the SARS- CoV-2 virus, endothelial dysfunction, coagulopathy, thrombus formation ...
V. A. Golovacheva +2 more
doaj +1 more source
Comprehensive Psychiatry, 2019 Background: Schizophrenia is a mental disorder characterized by hyperlocomotion, cognitive symptoms, and social withdrawal. Brain-derived neurotrophic factor (BDNF) and postsynaptic density (PSD)-95 are related to schizophrenia-like deficits via ...
Yue Xu +4 more
doaj +1 more source