Results 81 to 90 of about 1,667 (200)
Oxidative Medicine and Cellular Longevity, Volume 2025, Issue 1, 2025.Epilepsy is a neurological brain disease characterized by multiple seizures with short intervals and becomes drug‐resistant when it causes oxidative stress and inflammation in the brain. Ferulic acid (FA) is a plant phenolic substance with antioxidant, anti‐inflammatory, and neuroprotective effects that is used in the treatment of neurodegenerative ...
Elaheh Taheri +2 more
wiley +1 more source
Effects of Vinpocetine on mitochondrial function and neuroprotection in primary cortical neurons [PDF]
, 2008 Vinpocetine (ethyl apovincaminate), a synthetic derivative of the Vinca minor alkaloid vincamine, is widely used for the treatment of cerebrovascular-related diseases.
Nyakas, C., +14 more
core +1 more source
, 2020 Abnormal vascular smooth muscle cell (SMC) activation is associated with various vascular disorders such as atherosclerosis, in-stent restenosis, vein graft disease, and transplantationassociated vasculopathy.
Shujie Guo +6 more
core
[Mechanism of action of vinpocetine].
Acta pharmaceutica Hungarica, 1997 Cavinton was introduced into the clinical practice some twenty years ago in Hungary for the treatment of cerebrovascular disorders and related symptoms. Since then, its active ingredient, vinpocetine, beside its therapeutical utilization, has become a reference compound in the pharmacological research of cognitive deficits caused by hypoxia and ...
B, Kiss, E, Kárpáti
openaire +1 more source
CHRONIC BRAIN ISCHEMIA. CURRENT STATE OF THE PROBLEM
Медицинский совет, 2016 In the Russian literature the term dyscirculatory encephalopathy is most commonly used for designation of the chronic brain ischemia. The therapy of dyscirculatory encephalopathy is a problem that is far from resolution.
E. A. ANTIPENKO, A. V. GUSTOV
doaj +1 more source
The Mitochondrial Targets of Neuroprotective Drug Vinpocetine on Primary Neuron Cultures, Brain Capillary Endothelial Cells, Synaptosomes, and Brain Mitochondria [PDF]
, 2019 Vinpocetine is considered as neuroprotectant drug and used for treatment of brain ischemia and cognitive deficiencies for decades. A number of enzymes, channels and receptors can bind vinpocetine, however the mechanisms of many effects' are still not ...
Tretter, László +6 more
core +1 more source
Vinpocetine inhibits overt pain-like behavior.
, 2015 Panel A: mice were treated with vinpocetine (1, 3, 10, and 30 mg/kg, p.o.) or vehicle (saline) 1 h before acetic acid i.p. injection (0.6% v/v, diluted in saline).
Rubia Casagrande (714812) +5 more
core +1 more source
Zagazig Journal of Pharmaceutical Sciences, 2014 Cerebral ischaemia reperfusion (I/R) triggers a complex series of biochemical events that lead to formation of reactive oxygen species (ROS) and the impairment of enzymatic mechanisms, which result in tissue oxidative stress.
Abdel-Aal M +3 more
doaj +1 more source
A halláscsökkenés vinpocetin terápiája [PDF]
, 2016 Cél: a vinpocetin terápia halláscsökkenésben történő alkalmazásának bemutatása. Anyagok és módszerek: A szerzők összefoglalják az akut és idiopátiás percepciós típusú halláscsökkenésben alkalmazott, általuk használt kivizsgálási és terápiás protokollt.
Matievics Vera +3 more
openaire
Vinpocetine inhibits carrageenan-induced hyperalgesia and myeloperoxidase (MPO) activity.
, 2015 Mice were treated with vinpocetine (3, 10 or 30 mg/kg, p.o.) or vehicle (saline) 1 h before carrageenan (100 μg, 25 μL) i.pl. injection. Mechanical (Panel A) and thermal (Panel B) hyperalgesia were assessed at indicated time points after carrageenan ...
Rubia Casagrande (714812) +5 more
core +1 more source